4 Result(s)
within
English
Life Sciences
Computational Biology/Bioinformatics
Computer Appl. in Life Sciences
Systems Biology
Edda Klipp
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Article
Open AccessOsmolyte homeostasis controls single-cell growth rate and maximum cell size of Saccharomyces cerevisiae
Cell growth is well described at the population level, but precisely how nutrient and water uptake and cell wall expansion drive the growth of single cells is poorly understood. Supported by measurements of si...
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Article
Open AccessTranscriptional timing and noise of yeast cell cycle regulators—a single cell and single molecule approach
Gene expression is a stochastic process and its appropriate regulation is critical for cell cycle progression. Cellular stress response necessitates expression reprogramming and cell cycle arrest. While previo...
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Article
Open AccessA Clb/Cdk1-mediated regulation of Fkh2 synchronizes CLB expression in the budding yeast cell cycle
Precise timing of cell division is achieved by coupling waves of cyclin-dependent kinase (Cdk) activity with a transcriptional oscillator throughout cell cycle progression. Although details of transcription of...
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Article
Open AccessNetwork reconstruction and validation of the Snf1/AMPK pathway in baker’s yeast based on a comprehensive literature review
The SNF1/AMPK protein kinase has a central role in energy homeostasis in eukaryotic cells. It is activated by energy depletion and stimulates processes leading to the production of ATP while it downregulates A...
