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Article
Primary HIV-1 infection of human CD4+ T cells passaged into SCID mice leads to selection of chronically infected cells through a massive Fas-mediated autocrine suicide of uninfected cells
We have recently shown that a human CD4+ T cell line (CEM-SS) acquires the permissiveness to M-tropic strains and primary isolates of HIV-1 after transplantation into SCID mice. This permissiveness was associa...
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Chapter
Studies on the Expression of Spontaneous Interferon-Like Activity in Mouse Peritoneal Cells
Macrophages exert important functions in non specific natural resistance to virus infections (1–3). Several animal viruses do not multiply in macrophages when these cells are first placed in culture suggesting...
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Chapter
Interferon and Tumor Necrosis Factor Alter the Phospholipid Metabolism in Friend Leukemia Cell Tumors in Mice
Interferon (IFN) has been shown to inhibit the growth of different tumors in experimental animals (reviewed in 1 and 2) and it is currently used to treat some patients with cancer in clinical trials. However t...