35 Result(s)
within
E Lee
Medicine & Public Health
English
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Article
Comparative Analysis of Gait Speed Measurement Protocols: Static Start Versus Dynamic Start in a Cross-Sectional Study Using Light Detection and Ranging
There is currently no standardized protocol for the measurement of gait speed in older adults, particularly regarding the choice between static versus dynamic start.
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Article
Recurrence-free survival after total thyroidectomy and lobectomy in patients with papillary thyroid microcarcinoma
The incidence of papillary thyroid microcarcinoma is increasing. We evaluated the recurrence-free survival following total thyroidectomy and lobectomy to identify the optimal surgical choice.
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Article
Using opportunistic screening with abdominal CT to identify osteoporosis and osteopenia in patients with diabetes
Opportunistic osteoporosis screening involves measuring the attenuation of L1 vertebrae on abdominal computed tomography (CT), which correlates with DXA T-score. We found that this approach is useful for detec...
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Article
Open AccessImpact of Data Presentation on Physician Performance Utilizing Artificial Intelligence-Based Computer-Aided Diagnosis and Decision Support Systems
Ultrasound (US) is a valuable imaging modality used to detect primary breast malignancy. However, radiologists have a limited ability to distinguish between benign and malignant lesions on US, leading to false...
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Article
Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma
The SMOOTHENED inhibitor vismodegib is FDA approved for advanced basal cell carcinoma (BCC), and shows promise in clinical trials for SONIC HEDGEHOG (SHH)-subgroup medulloblastoma (MB) patients. Clinical exper...
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The impact of mode of presentation on distress in patients with early stage breast cancer
We set out to determine whether a difference exists between levels of psychological distress in women diagnosed with breast cancer through routine screening versus those who presented symptomatically.
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Article
Open AccessESICM LIVES 2016: part two
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Article
Open AccessMeditation and vacation effects have an impact on disease-associated molecular phenotypes
Meditation is becoming increasingly practiced, especially for stress-related medical conditions. Meditation may improve cellular health; however, studies have not separated out effects of meditation from vacat...
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Novel effects of sarcopenic osteoarthritis on metabolic syndrome, insulin resistance, osteoporosis, and bone fracture: the national survey
This study compared the effects sarcopenic osteoarthritis on metabolic syndrome, insulin resistance, osteoporosis, and bone fracture. By using national survey data, we suggest that the relationship between sar...
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Health-related quality of life of Asian patients with end-stage renal disease (ESRD) in Singapore
This study aimed to identify factors associated with the health-related quality of life (HRQOL) of multiethnic Asian end-stage renal disease (ESRD) patients treated with dialysis. The role of dialysis modality...
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Article
Progress of PTSD symptoms following birth: a prospective study in mothers of high-risk infants
To understand how postpartum posttraumatic stress disorder (PTSD) symptoms in mothers of high-risk infants progress and identify what factors predict postpartum PTSD.
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Article
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias
High expression of the ETS family transcription factor ERG is associated with poor clinical outcome in acute myeloid leukemia (AML) and acute T-cell lymphoblastic leukemia (T-ALL). In murine models, high ERG e...
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Article
Synthetic lethal screening reveals FGFR as one of the combinatorial targets to overcome resistance to Met-targeted therapy
Met is a receptor tyrosine kinase that promotes cancer progression. In addition, Met has been implicated in resistance of tumors to various targeted therapies such as epidermal growth factor receptor inhibitor...
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Article
A role for oleoylethanolamide in chronic lymphocytic leukemia
Oleoylethanolamide (OEA) is a bioactive lipid that stimulates nuclear and G protein-coupled receptors and regulates appetite and fat metabolism. It has not previously been shown to have a role in cancer. Howev...
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Article
Estimating risks for variants of unknown significance according to their predicted pathogenicity classes with application to BRCA1
Sequence-based testing of disease-susceptibility genes has identified many variants of unknown significance (VUSs) whose pathogenicity is unknown at the time of their measurement. Female breast cancer cases ag...
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Article
Characteristics of rhegmatogenous retinal detachment and their relationship to visual outcome
To examine pre-operative characteristics of rhegmatogenous retinal detachment (RRD) and their relationship to visual acuity (VA) following surgery.
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Article
PPAR-alpha is a therapeutic target for chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) cells with aggressive clinical properties express lipoprotein lipase (LPL), which generates activating ligands for the nuclear receptor peroxisome proliferator activated rece...
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Article
Identification of a pivotal endocytosis motif in c-Met and selective modulation of HGF-dependent aggressiveness of cancer using the 16-mer endocytic peptide
Since c-Met has an important role in the development of cancer, it is considered as an attractive target for cancer therapy. Although molecular mechanisms for oncogenic property of c-Met have been actively inv...
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Comment on ‘Silicone oil removal after rhegmatogenous retinal detachment: comparing techniques’
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Article
Open Access1.2: Differential Impacts of Hypertension and Type 2 Diabetes Mellitus on Arterial Disease and Cardiovascular Outcomes: The Strong Heart Study
Both hypertension and diabetes mellitus (DM) increase risk for subclinical and clinical cardiovascular disease (CVD). The relative extents to which hypertension and DM induce subclinical CVD have not been exam...
