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    HDAC inhibition impedes epithelial–mesenchymal plasticity and suppresses metastatic, castration-resistant prostate cancer

    PI3K (phosphoinositide 3-kinase)/AKT and RAS/MAPK (mitogen-activated protein kinase) pathway coactivation in the prostate epithelium promotes both epithelial–mesenchymal transition (EMT) and metastatic castrat...

    M Ruscetti, E L Dadashian, W Guo, B Quach, D J Mulholland, J W Park, L M Tran… in Oncogene (2016)