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Open AccessImplications of iron deficiency/anemia on the classification of diabetes using HbA1c
Nonglycemic factors like iron deficiency (ID) or anemia may interfere with classification of diabetes and prediabetes using hemoglobin A1c (HbA1c). However, few population-based studies of diabetes in areas wi...
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Article
Open AccessGenetic risk score and adiposity interact to influence triglyceride levels in a cohort of Filipino women
Individually, genetic variants only moderately influence cardiometabolic (CM) traits, such as lipid and inflammatory markers. In this study we generated genetic risk scores from a combination of previously rep...
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Open AccessChange in DASH diet score and cardiovascular risk factors in youth with type 1 and type 2 diabetes mellitus: The SEARCH for Diabetes in Youth Study
Youth with diabetes are at an increased risk of cardiovascular disease (CVD). Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet has been shown to improve CVD risk. In this study, we evaluate...
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Clinical evolution of beta cell function in youth with diabetes: the SEARCH for Diabetes in Youth study
Few studies have explored the epidemiology of beta cell loss in youth with diabetes. This report describes the evolution and major determinants of beta cell function, assessed by fasting C-peptide (FCP), in th...
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Open AccessMultilevel examination of diabetes in modernising China: what elements of urbanisation are most associated with diabetes?
The purpose of this study was to examine the association between urbanisation-related factors and diabetes prevalence in China.
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Association testing of TCF7L2 polymorphisms with type 2 diabetes in multi-ethnic youth
Common variants in the transcription factor 7-like 2 (TCF7L2) gene have been associated with type 2 diabetes in adults. However, it is not known whether TCF7L2 variation increases the risk of early onset type 2 d...
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Development, validation and use of an insulin sensitivity score in youths with diabetes: the SEARCH for Diabetes in Youth study
The ability to measure insulin sensitivity across the phenotypic spectrum of diabetes may contribute to a more accurate characterisation of diabetes type. Our goal was to develop and validate an insulin sensit...
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40th EASD Annual Meeting of the European Association for the Study of Diabetes
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Familial components of the multiple metabolic syndrome: the ARIC Study
The association of a parental history of diabetes mellitus and hypertension with the multiple metabolic syndrome (MMS) was studied in a population survey of middle-aged adults. The eligible population was dra...