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15 Result(s)

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  1. Article

    Open Access

    Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration

    6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) is a master regulator of glycolysis by its ability to synthesize fructose-2,6-bisphosphate, a potent allosteric activator of 6-phosphofructo-1-ki...

    P Rodriguez-Rodriguez, E Fernandez, A Almeida, J P Bolaños in Cell Death & Differentiation (2012)

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  2. No Access

    Article

    Chemical modifiers for direct determination of cobalt in coal combustion residues by ultrasonic slurry-sampling–ETAAS

    Five modifiers were tested for the direct determination of cobalt in coal fly ash and slag by ultrasonic slurry-sampling electrothermal atomic absorption spectrometry (USS–ETAAS).The furnace temperature progra...

    M. Felipe-Sotelo, A. Carlosena, E. Fernández… in Fresenius' Journal of Analytical Chemistry (2001)

  3. No Access

    Article

    On the validity of the two-cells model in the analysis of passive electrical properties of gap-junction connected cells

    It is a rather extended practice to derive electrophysiological data (membrane and contact conductances) from experimental data for gap-junction tissues assuming that electrical connections are reduced to cel...

    E. Andreu, E. Fernandez, E. Louis, G. Ortega… in European Biophysics Journal (2001)

  4. No Access

    Article

    Eukaryotic nitrate and nitrite transporters

    Nitrate transport is the key step controlling the amount of nitrate incorporated by the cells and subsequent of storage, reduction or export. Molecular, genetic and biochemical approaches to the study of euka...

    A. Galván, E. Fernández* in Cellular and Molecular Life Sciences CMLS (2001)

  5. No Access

    Article

    Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus

    A 2580-bp region of the chromosome of Streptomyces argillaceus, the producer of the antitumor polyketide mithramycin, was sequenced. Analysis of the nucleotide sequence revealed the presence of two genes (mtmGII...

    G. Blanco, E. Fernández, M. J. Fernández, A. F. Braña… in Molecular and General Genetics MGG (2000)

  6. No Access

    Article

    Medical Conditions in Patients with Pancreatic and Biliary Diseases (Validity and Agreement Between Data from Questionnaires and Medical Records)

    The aims of the study were to assess theagreement between data from personal interviews andmedical records on selected medical conditions, toevaluate the validity of each source of information, andto estimate ...

    M. Soler, N. Malats, M. Porta, E. Fernandez, L. Guarner… in Digestive Diseases and Sciences (1999)

  7. No Access

    Article

    Three Nrt2 genes are differentially regulated in Chlamydomonas reinhardtii

    Two new nitrate assimilation-related genes, Nrt2;3 and Nar5, have been identified in Chlamydomonas reinhardtii. The Nrt2;3 gene is a new member of the Nrt2 family, encoding high-affinity nitrate (nitrite) transp...

    A. Quesada, J. Hidalgo, E. Fernández in Molecular and General Genetics MGG (1998)

  8. No Access

    Chapter

    Lichen’s Adaptation to Altitude

    Lichens from alpine regions and from areas of high altitudes are subject to the effects of high UV radiation levels, which have increased in the last decades due to the decrease of ozone, and they have develop...

    E. Fernández, W. Quilhot, C. Rubio, E. Barre in Photosynthesis: Mechanisms and Effects (1998)

  9. No Access

    Article

    An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producerStreptomyces argillaceus

    Mithramycin is an antitumor antibiotic synthesized byStreptomyces argillaceus. This producer strain is highly resistant in vivo to mithramycin (MIC 100 µg/ml) but sensitive to the related drugs chromomycin and ol...

    E. Fernández, F. Lombó, C. Méndez, J. A. Salas in Molecular and General Genetics MGG (1996)

  10. No Access

    Article

    Isolation and characterization of two new negative regulatory mutants for nitrate assimilation inChlamydomonas reinhardtii obtained by insertional mutagenesis

    Plasmid DNA carrying either the nitrate reductase (NR) gene or the argininosuccinate lyase gene as selectable markers and the correspondingChlamydomonas reinhardtii mutants as recipient strains have been used to ...

    R. Prieto, A. Dubus, A. Galván, E. Fernández in Molecular and General Genetics MGG (1996)

  11. No Access

    Chapter

    Intravenous Potassium Infusion Reverses Skeletal Muscle Fatigue

    Intracellular potassium loss has been implicated as the basis of skeletal muscle fatigue (1). A decrease in the cell membrane K+ gradient diminishes the action potential. In turn, Ca++ release decreases and a sma...

    R. Kiiski, E. Fernandez, G. Gutierrez in Oxygen Transport to Tissue XVI (1994)

  12. No Access

    Article

    Tris discriminates between the different α-glucosidase activities from extracts of human neutrophils

    In an attempt to detect acid maltase deficiency in neutrophils from patients with type II glycogenosis, without interference from the ‘renal’ α-glucosidase activity present in these cells, we have evaluated th...

    M. Asunción Ortiz de Apodaca, E. Fernandez… in Journal of Inherited Metabolic Disease (1992)

  13. No Access

    Chapter and Conference Paper

    Molecular Biology of Nitrate Assimilation in Chlamydomonas ReinhardtII

    As in other photosynthetic eukaryotes, nitrate assimilation in the green alga Chlamydomonas is a highly regulated process which requires transport of the anion into the cell and its reduction to ammonium catalyze...

    E. Fernández, R. Sehnell, L. P. W. Ranum… in Inorganic Nitrogen in Plants and Microorga… (1990)

  14. Article

    A mutant of Chlamydomonas reinhardtii altered in the transfort of ammonium and methylammonium

    A. R. Franco, J. Cárdenas, E. Fernández in Molecular and General Genetics MGG (1987)

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  15. Article

    A mutant of Chlamydomonas reinhardtii altered in the transport of ammonium and methylammonium

    A. R. Franco, G. Cárdenas, E. Fernández in Molecular and General Genetics MGG (1987)

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