3 Result(s)
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Dunming **ao
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessDiffDomain enables identification of structurally reorganized topologically associating domains
Topologically associating domains (TADs) are critical structural units in three-dimensional genome organization of mammalian genome. Dynamic reorganizations of TADs between health and disease states are associ...
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Article
Open AccessFind_tfSBP: find thermodynamics-feasible and smallest balanced pathways with high yield from large-scale metabolic networks
Biologically meaningful metabolic pathways are important references in the design of industrial bacterium. At present, constraint-based method is the only way to model and simulate a genome-scale metabolic net...
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Article
Open AccessNew recombinant cyclohexylamine oxidase variants for deracemization of secondary amines by orthogonally assaying designed mutants with structurally diverse substrates
To further expand the substrate range of the cyclohexylamine oxidase (CHAO) from Brevibacterium oxydans, a library of diverse mutants was created and assayed toward a group of structurally diverse substrates. Amo...
