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  1. Article

    Reactivity of Metabolic Intermediates and Cofactor Stability under Model Early Earth Conditions

    Understanding the emergence of metabolic pathways is key to unraveling the factors that promoted the origin of life. One popular view is that protein cofactors acted as catalysts prior to the evolution of the ...

    Thora R. Maltais, David VanderVelde… in Origins of Life and Evolution of Biospheres (2020)

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  2. Article

    Open Access

    Thermodynamic Potential for the Abiotic Synthesis of Adenine, Cytosine, Guanine, Thymine, Uracil, Ribose, and Deoxyribose in Hydrothermal Systems

    The thermodynamic potential for the abiotic synthesis of the five common nucleobases (adenine, cytosine, guanine, thymine, and uracil) and two monosaccharides (ribose and deoxyribose) from formaldehyde and hyd...

    Douglas E. LaRowe, Pierre Regnier in Origins of Life and Evolution of Biospheres (2008)

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  3. Article

    Hydrothermal Stability of Adenine Under Controlled Fugacities of N2, CO2 and H2

    An experimental study has been carried out on the stability of adenine (one of the five nucleic acid bases) under hydrothermal conditions. The experiments were performed in sealed autoclaves at 300°C under fug...

    Michael Franiatte, Laurent Richard… in Origins of Life and Evolution of Biospheres (2008)

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