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Article
Open AccessMF-MNER: Multi-models Fusion for MNER in Chinese Clinical Electronic Medical Records
To address the problem of poor entity recognition performance caused by the lack of Chinese annotation in clinical electronic medical records, this paper proposes a multi-medical entity recognition method F-MN...
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Article
Open AccessWGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis
Doxorubicin (DOX)-induced cardiotoxicity (DIC) is a major impediment to its clinical application. It is indispensable to explore alternative treatment molecules or drugs for mitigating DIC. WGX50, an organic e...
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Article
Open AccessIntegrated models of blood protein and metabolite enhance the diagnostic accuracy for Non-Small Cell Lung Cancer
For early screening and diagnosis of non-small cell lung cancer (NSCLC), a robust model based on plasma proteomics and metabolomics is required for accurate and accessible non-invasive detection. Here we aim t...
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Article
Discovery of a Natural Product with Potent Efficacy Against SARS-CoV-2 by Drug Screening
The novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide for almost 2 years. It starts from viral adherence to host cells throug...
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Article
Open AccessStoichioproteomics reveal oxygen usage bias, key proteins and pathways in glioma
The five-year survival rate and therapeutic effect of malignant glioma is low. Identification of key/associated proteins and pathways in glioma is necessary for develo** effective diagnosis and targeted ther...
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Article
Open AccessAuthor Correction: Pressure-Induced Crystallization and Phase Transformation of Para-xylene
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
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Article
Open AccessPressure-Induced Crystallization and Phase Transformation of Para-xylene
Static pressure is an alternative method to chemical pressure for tuning the crystal structure, bonds, and physical properties of materials, and is a significant technique for the synthesis of novel materials ...
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Exploring the Ligand-Protein Networks in Traditional Chinese Medicine: Current Databases, Methods and Applications
While the concept of “single component–single target” in drug discovery seems to have come to an end, “Multi-component–multi-target” is considered to be another promising way out in this field. The Traditional...
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Article
Genetic insight of the H5N1 hemagglutinin cleavage site
The cleavability of the hemagglutinin (HA) plays a major role in virulence of avian influenza viruses. Detailed analyses of the cleavage sequences and their evolution would give insights into the high pathogen...