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Article
The grapevine miR827a regulates the synthesis of stilbenes by targeting VqMYB14 and gives rise to susceptibility in plant immunity
Grapevine (Vitis vinifera L.) is an economically important fruit crop cultivated worldwide. In China, grapevine cultivation is very extensive, and a few Vitis grapes have excellent pathogen and stress resistance,...
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Article
Comparison of the Effects of pH-Shifting, Acetic Acid Modification, and TGase Treatment on the Physicochemical and Functional Properties of Wheat Gluten Protein
Wheat gluten protein (WGP) is a fine-quality plant-based protein resource. However, as its unparalleled reticulation structure, the processing properties of WGP are extremely poor, limiting its application. To...
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Article
Sodium Butyrate Ameliorates Fluorosis-Induced Neurotoxicity by Regulating Hippocampal Glycolysis In Vivo
Fluorosis can induce neurotoxicity. Sodium butyrate (SB), a histone deacetylase inhibitor, has important research potential in correcting glucose metabolism disorders and is widely used in a variety of neurolo...
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Article
Enhanced biomass production and wastewater treatment in attached co-culture of Chlorella pyrenoidosa with nitrogen-fixing bacteria Azotobacter beijerinckii
Algae–bacteria symbiosis can promote the growth of microalgae and improve the efficiency of wastewater treatment. Attached culture is an efficient culture technique for microalgae, with benefits of high yield,...
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Article
A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo
Endocannabinoids (eCBs) are retrograde neuromodulators with important functions in a wide range of physiological processes, but their in vivo dynamics remain largely uncharacterized. Here we developed a geneti...
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Article
Automatic system for high-throughput and high-sensitivity diagnosis of SARS-CoV-2
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had severe consequences for health and the global economy. To control the transmissio...
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Article
Azospirillum tabaci sp. nov., a bacterium isolated from rhizosphere soil of Nicotiana tabacum L
Strain W712T was isolated from rhizosphere soil of Nicotiana tabacum L. collected from Kunming, south-west China. Cells were Gram-staining negative, aerobic, motile and rod shaped. The isolate grew at 20–45 °C (o...
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Article
RNA demethylation increases the yield and biomass of rice and potato plants in field trials
RNA N6-methyladenosine (m6A) modifications are essential in plants. Here, we show that transgenic expression of the human RNA demethylase FTO in rice caused a more than threefold increase in grain yield under gre...
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Article
Two-dimensional van der Waals thin film transistors as active matrix for spatially resolved pressure sensing
The development of pressure sensor arrays capable of distinguishing the shape and texture details of objects is of considerable interest in the emerging fields of smart robots, prostheses, human-machine interf...
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Article
Chthonobacter rhizosphaerae sp. nov., a bacterium isolated from rhizosphere soil of Citrus sinenesis
A Gram-staining negative, facultative anaerobic, motile and short rod-shaped bacterium, designated strain yh7-1T, was isolated from rhizosphere soil of Citrus sinenesis collected from the garden of Citrus sinenes...
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Article
Open AccessThe targetable nanoparticle BAF312@cRGD-CaP-NP represses tumor growth and angiogenesis by downregulating the S1PR1/P-STAT3/VEGFA axis in triple-negative breast cancer
Overexpressed vascular endothelial growth factor A (VEGFA) and phosphorylated signal transducer and activator of transcription 3 (P-STAT3) cause unrestricted tumor growth and angiogenesis of breast cancer (BRC...
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Article
A chemically stable nanoporous coordination polymer with fixed and free Cu2+ ions for boosted C2H2/CO2 separation
Safely and highly selective acetylene (C2H2) capture is a great challenge, because of its highly explosive nature, as well as its nearly similar molecule size and boiling point toward the main impurity of carbon ...
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Article
Open AccessEngineering endogenous ABC transporter with improving ATP supply and membrane flexibility enhances the secretion of β-carotene in Saccharomyces cerevisiae
Product toxicity is one of the bottlenecks for microbial production of biofuels, and transporter-mediated biofuel secretion offers a promising strategy to solve this problem. As a robust microbial host for ind...
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Article
Infant cardiosphere-derived cells exhibit non-durable heart protection in dilated cardiomyopathy rats
Stem cells provide a new strategy for the treatment of cardiac diseases; however, their effectiveness in dilated cardiomyopathy (DCM) has not been investigated. In this study, cardiosphere-derived cells (CDCs)...
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Article
Open AccessMicrogravity disturbance analysis on Chinese space laboratory
Many scientific experiments are conducted in space; therefore, it is critical to understand the microgravity environment of a space laboratory. The first Chinese cargo ship, Tianzhou-1 (TZ-1), entered space on...
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Article
Open AccessConversion of a rice CMS maintainer into a photo- or thermo-sensitive genetic male sterile line
A maintainer line of 3-line hybrid rice commonly presents a certain genetic distance to a 2-line restorer line, but in many cases, 2-line restorer lines present defects upon recovery of the object cytoplasmic ...
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Article
Strain improvement by combined UV mutagenesis and ribosome engineering and subsequent fermentation optimization for enhanced 6′-deoxy-bleomycin Z production
The bleomycins (BLMs) are important clinical drugs extensively used in combination chemotherapy for the treatment of various cancers. Dose-dependent lung toxicity and the development of drug resistance have re...
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Article
Mechanochemistry synthesis of high purity lithium carbonate
A technique for preparing high purity Li2CO3 powders has been developed through mechanochemical process coupled with the dissolution-filtration process. The first step as mechanochemical reaction of both Na2CO3 a...
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Article
Quantitative Proteome Profiling of Street Rabies Virus-Infected Mouse Hippocampal Synaptosomes
It is well established now that neuronal dysfunction rather than structural damage may be responsible for the development of rabies. In order to explore the underlying mechanisms in rabies virus (RABV) and syn...
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Article
A novel er1 allele and the development and validation of its functional marker for breeding pea (Pisum sativum L.) resistance to powdery mildew
A novel er1 allele, er1 -7, conferring pea powdery mildew resistance was characterized by a 10-bp deletion in ...