3,664 Result(s)

Article

The overexpression of DSP1 in neurons induces neuronal dysfunction and neurodegeneration phenotypes in Drosophila

Dorsal switch protein 1(DSP1), a mammalian homolog of HMGB1, is firstly identified as a dorsal co-repressor in 1994. DSP1 contains HMG-box domain and functions as a transcriptional regulator in Drosophila melanog...

Si-Eun Baek, Younghwi Kwon, Jong-Won Yoon, Hyo-Sung Kim, Jae-Yoon Yang… in Molecular Brain (2024)

Article

Sodium tanshinone IIA sulfonate protects vascular relaxation in ApoE-knockout mice by inhibiting the SYK-NLRP3 inflammasome-MMP2/9 pathway

Hyperlipidemia damages vascular wall and serves as a foundation for diseases such as atherosclerosis, hypertension and stiffness. The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is ...

Hai-Hua Liu, Wei Wei, Fei-Fei Wu, Lu Cao, Bing-Jie Yang… in BMC Cardiovascular Disorders (2024)

Article

The type III effector NopL interacts with GmREM1a and GmNFR5 to promote symbiosis in soybean

The establishment of symbiotic interactions between leguminous plants and rhizobia requires complex cellular programming activated by Rhizobium Nod factors (NFs) as well as type III effector (T3E)-mediated sym...

Chao Ma, **hui Wang, Yongkang Gao, Xulun Dong, Haojie Feng… in Nature Communications (2024)

Article

Search for the \( {B}_s^0 \) → μ⁺μ⁻γ decay

A search for the fully reconstructed B s 0 ...

R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta… in Journal of High Energy Physics (2024)

Article

Early detection of low QRS voltage and its association with mortality in patients with sepsis

Various electrocardiographic changes occur during sepsis, but data on the clinical importance of a low QRS voltage in sepsis are still limited. We aimed to evaluate the association between low QRS voltage iden...

Soo ** Na, Ryoung-Eun Ko, Chi Ryang Chung, Jeong Hoon Yang… in Scientific Reports (2024)

Article

Measurement of e⁺e⁻ → ωη′ cross sections at \( \sqrt{s} \) = 2.000 to 3.080 GeV

We measured the Born cross sections for the process e⁺e⁻ → ωη′ at 22 center-of-mass energies from 2.000 to 3.080 GeV with the BESIII detector at the BEPCII collider. We observed a resonant structure with a statis...

M. Ablikim, M. N. Achasov, P. Adlarson, X. C. Ai… in Journal of High Energy Physics (2024)

Article

Wild rodents seed choice is relevant for sustainable agriculture

Mitigating pre-harvest sprouting (PHS) and post-harvest food loss (PHFL) is essential for enhancing food securrity. To reduce food loss, the use of plant derived specialized metabolites can represent a good ap...

Yang Peng, Zhenbang Hu, Wen Dong, **aodong Wu, Chunyan Liu… in Scientific Reports (2024)

Article

Malignant solitary fibrous tumor of the kidney with IGF2 secretion and without hypoglycemia

Solitary fibrous tumor (SFT) is a rare fibroblastic mesenchymal tumor that mostly involves the pleura and infrequently involves extra-pleural sites. De novo SFT of the kidney is uncommon, and malignant SFT is ...

Luting Zhou, Yang Liu, Teng Xu, Lei Dong… in World Journal of Surgical Oncology (2024)

Article

Design of 3D printing osteotomy block for foot based on triply periodic minimal surface

The ankle joint, which connects the lower limbs and the sole of the foot, is prone to sprain during walking and sports, which leads to ankle arthritis. Supratroleolar osteotomy is an ankle preserving operation...

Hai-qiong **e, Hai-tao **e, Tao Luo, Bai-yin Yang, Dao-qi Gan… in Scientific Reports (2024)

Article

Deep Learning–Based Localization and Detection of Malpositioned Nasogastric Tubes on Portable Supine Chest X-Rays in Intensive Care and Emergency Medicine: A Multi-center Retrospective Study

Malposition of a nasogastric tube (NGT) can lead to severe complications. We aimed to develop a computer-aided detection (CAD) system to localize NGTs and detect NGT malposition on portable chest X-rays (CXRs)...

Chih-Hung Wang, Tianyu Hwang, Yu-Sen Huang… in Journal of Imaging Informatics in Medicine (2024)

Article

Serum matrix metalloproteinase-7 for discriminating biliary atresia: a diagnostic accuracy and validation study

Prompt and precise differential diagnosis of biliary atresia (BA) among cholestatic patients is of great importance. Matrix metalloproteinase-7 (MMP-7) holds great promise as a diagnostic marker for BA. This s...

**gying Jiang, Rui Dong, Min Du, Gong Chen… in Journal of Translational Medicine (2024)

Article

Peroxiredoxin 1 inhibits streptozotocin-induced Alzheimer’s disease-like pathology in hippocampal neuronal cells via the blocking of Ca²⁺/Calpain/Cdk5-mediated mitochondrial fragmentation

Oxidative stress plays an essential role in the progression of Alzheimer’s disease (AD), the most common age-related neurodegenerative disorder. Streptozotocin (STZ)-induced abnormal brain insulin signaling an...

Junghyung Park, **young Won, Eunyeoung Yang, **cheol Seo… in Scientific Reports (2024)

Article

Multi-omics differences in the bone marrow between essential thrombocythemia and prefibrotic primary myelofibrosis

Essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre-PMF) are Philadelphia chromosome-negative myeloproliferative neoplasms. These conditions share overlap** clinical presentations; howe...

Anqi Zhang, Ting Sun, Dandan Yu, Rongfeng Fu… in Clinical and Experimental Medicine (2024)

Article

Telomere-to-telomere genome assembly of the goose Anser cygnoides

Our study presents the assembly of a high-quality Taihu goose genome at the Telomere-to-Telomere (T2T) level. By employing advanced sequencing technologies, including Pacific Biosciences HiFi reads, Oxford Nan...

Hongchang Zhao, Hao Zhou, Guobo Sun, Biao Dong, Wenqi Zhu, **aohui Mu… in Scientific Data (2024)

Article

Aggregation promotes charge separation in fullerene-indacenodithiophene dyad

Fast photoinduced charge separation (CS) and long-lived charge-separated state (CSS) in small-molecules facilitate light-energy conversion, while simultaneous attainment of both remains challenging. Here we ac...

Chong Wang, Bo Wu, Yang Li, Shen Zhou, Conghui Wu, Tianyang Dong… in Nature Communications (2024)

Article

Genome-wide analysis of MYB transcription factor family and AsMYB1R subfamily contribution to ROS homeostasis regulation in Avena sativa under PEG-induced drought stress

The myeloblastosis (MYB) transcription factor (TF) family is one of the largest and most important TF families in plants, playing an important role in a life cycle and abiotic stress.

Yang Chen, Aixue Li, ** Yun, Quan Chen, Dayu Pan, Rui Guo, Han Zhang… in BMC Plant Biology (2024)

Article

ATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8⁺ T cells

Obesity shapes anti-tumor immunity through lipid metabolism; however, the mechanisms underlying how colorectal cancer (CRC) cells utilize lipids to suppress anti-tumor immunity remain unclear. Here, we show th...

Tu-**ong Huang, Hui-Si Huang, Shao-Wei Dong, Jia-Yan Chen… in Nature Communications (2024)

Article

Deep learning for multi-type infectious keratitis diagnosis: A nationwide, cross-sectional, multicenter study

The main cause of corneal blindness worldwide is keratitis, especially the infectious form caused by bacteria, fungi, viruses, and Acanthamoeba. The key to effective management of infectious keratitis hinges o...

Zhongwen Li, He **e, Zhouqian Wang, Daoyuan Li, Kuan Chen… in npj Digital Medicine (2024)

Article

Controlled Twill Surface Structure Endowing Nanofiber Composite Membrane Excellent Electromagnetic Interference Shielding

Article

Author Correction: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice

Tao Zhuang, Mei-Hua Chen, Ruo-** Wu, **g Wang, **-De Hu… in Nature Communications (2024)