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Open AccessHigh-density vertical sidewall MoS2 transistors through T-shape vertical lamination
Vertical transistors, in which the source and drain are aligned vertically and the current flow is normal to the wafer surface, have attracted considerable attention recently. However, the realization of high-...
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Article
Open AccessTelomere-to-telomere Citrullus super-pangenome provides direction for watermelon breeding
To decipher the genetic diversity within the cucurbit genus Citrullus, we generated telomere-to-telomere (T2T) assemblies of 27 distinct genotypes, encompassing all seven Citrullus species. This T2T super-pangeno...
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Article
Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability
The impairment of blood-brain barrier (BBB) integrity is the pathological basis of hemorrhage transformation and vasogenic edema following thrombolysis and endovascular therapy. There is no approved drug in th...
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Article
Open AccessASD-SWNet: a novel shared-weight feature extraction and classification network for autism spectrum disorder diagnosis
The traditional diagnostic process for autism spectrum disorder (ASD) is subjective, where early and accurate diagnosis significantly affects treatment outcomes and life quality. Thus, improving ASD diagnostic...
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Article
Open AccessShared genetic effect of kidney function on bipolar and major depressive disorders: a large-scale genome-wide cross-trait analysis
Epidemiological studies have revealed a significant association between impaired kidney function and certain mental disorders, particularly bipolar disorder (BIP) and major depressive disorder (MDD). However, ...
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Article
Monolithic three-dimensional tier-by-tier integration via van der Waals lamination
Two-dimensional (2D) semiconductors have shown great potential for monolithic three-dimensional (M3D) integration due to their dangling-bonds-free surface and the ability to integrate to various substrates wit...
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Article
On Minor Left Prime Factorization Problem for Multivariate Polynomial Matrices
A new necessary and sufficient condition for the existence of minor left prime factorizations of multivariate polynomial matrices without full row rank is presented. The key idea is to establish a relationship...
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Article
Open AccessTwo-dimensional materials for future information technology: status and prospects
Over the past 70 years, the semiconductor industry has undergone transformative changes, largely driven by the miniaturization of devices and the integration of innovative structures and materials. Two-dimensi...
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Article
Open AccessLiver ACOX1 regulates levels of circulating lipids that promote metabolic health through adipose remodeling
The liver gene expression of the peroxisomal β-oxidation enzyme acyl-coenzyme A oxidase 1 (ACOX1), which catabolizes very long chain fatty acids (VLCFA), increases in the context of obesity, but how this pathw...
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Open AccessThe value of cardiopulmonary comorbidity in patients with acute large vessel occlusion stroke undergoing endovascular thrombectomy: a retrospective, observational cohort study
Chronic lung and heart diseases are more likely to lead an intensive end point after stroke onset. We aimed to investigate characteristics and outcomes of endovascular thrombectomy (EVT) in patients with acute...
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Open AccessAuthor Correction: Multiple factors and features dictate the selective production of ct-siRNA in Arabidopsis
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Molecular Engineering to Achieve AIE-active Fluorophore with Near-infrared (NIR) Emission and Temperature-sensitive Property
Near-infrared organic small molecule luminescent materials have the advantages of easy modification, high quantum efficiency, good biological affinity, and color adjustability; thus, have promising application...
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Article
Controlled large-area lithium deposition to reduce swelling of high-energy lithium metal pouch cells in liquid electrolytes
Lithium (Li) metal battery technology, renowned for its high energy density, faces practical challenges, particularly concerning large volume change and cell swelling. Despite the profound impact of external p...
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Open AccessTelomerase is essential for cardiac differentiation and sustained metabolism of human cardiomyocytes
Telomeres as the protective ends of linear chromosomes, are synthesized by the enzyme telomerase (TERT). Critically short telomeres essentially contribute to aging-related diseases and are associated with a br...
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Article
Open AccessCircular RNA circZFPM2 regulates cardiomyocyte hypertrophy and survival
Hypertrophic cardiomyopathy (HCM) constitutes the most common genetic cardiac disorder. However, current pharmacotherapeutics are mainly symptomatic and only partially address underlying molecular mechanisms. ...
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Article
Open AccessMultiple factors and features dictate the selective production of ct-siRNA in Arabidopsis
Coding transcript-derived siRNAs (ct-siRNAs) produced from specific endogenous loci can suppress the translation of their source genes to balance plant growth and stress response. In this study, we generated Arab...
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Article
Open AccessEvaluation of models to predict prognosis in patients with advanced hepatocellular carcinoma treated with TACE combined with apatinib
The HAP, Six-and-Twelve, Up to Seven, and ALBI scores have been substantiated as reliable prognostic markers in patients presenting with intermediate and advanced hepatocellular carcinoma (HCC) undergoing tran...
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Article
Distributed Photovoltaic Real-Time Output Estimation Based on Graph Convolutional Networks
The rapid growth of distributed photovoltaic (PV) has remarkable influence for the safe and economic operation of power systems. In view of the wide geographical distribution and a large number of distributed ...
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Article
Real-Time Safety Behavior Detection Technology of Indoors Power Personnel Based on Human Key Points
Safety production is of great significance to the development of enterprises and society. Accidents often cause great losses because of the particularity environment of electric power. Therefore, it is importa...
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Article
Non-Fermi liquid behaviour in a correlated flat-band pyrochlore lattice
Electronic correlation effects are manifested in quantum materials when either the on-site Coulomb repulsion is large or the electron kinetic energy is small. The former is the dominant effect in cuprate super...
