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  1. Article

    Open Access

    Different association of atherogenic index of plasma with the risk of high platelet reactivity according to the presentation of acute myocardial infarction

    This study evaluated the association of atherogenic index of plasma (AIP) with platelet reactivity and clinical outcomes according to acute myocardial infarction (AMI). The composite of 3-year adverse outcomes...

    Ki-Bum Won, Hyeon Jeong Kim, Jun Hwan Cho, Sang Yup Lee, Ae-Young Her in Scientific Reports (2024)

  2. Article

    Open Access

    High platelet reactivity strongly predicts early stent thrombosis in patients with drug-eluting stent implantation

    Stent thrombosis (ST) is a fatal complication after percutaneous coronary intervention (PCI). The association between P2Y12 reaction unit (PRU) level and stent thrombosis occurrence remains unclear. Based on t...

    Subin Lim, Soon Jun Hong, Ju Hyeon Kim, Jung-Joon Cha, Hyung Joon Joo in Scientific Reports (2024)

  3. Article

    Open Access

    Implication of diabetic status on platelet reactivity and clinical outcomes after drug-eluting stent implantation: results from the PTRG-DES consortium

    Diabetes mellitus (DM) is associated with thrombogenicity, clinically manifested with atherothrombotic events after percutaneous cutaneous intervention (PCI). This study aimed to investigate association betwee...

    Ki-Hyun Jeon, Young-Hoon Jeong, In-Ho Chae, Byeong-Keuk Kim in Cardiovascular Diabetology (2023)

  4. Article

    Open Access

    Correction: Comparison of 2‑year mortality according to obesity in stabilized patients with type 2 diabetes mellitus after acute myocardial infarction: results from the DIAMOND prospective cohort registry

    Ki‑Bum Won, Seung‑Ho Hur, Yun‑Kyeong Cho, Hyuck‑Jun Yoon in Cardiovascular Diabetology (2023)

  5. No Access

    Article

    Identifying fragile calcifications of the aortic valve in transcatheter aortic valve replacement: iodine concentration of aortic valvular calcification by spectral CT

    To demonstrate the relationship between spectral computed tomography (CT) measured iodine concentration and strength of aortic valvular calcification (AVC) in patients with aortic valve stenosis (AVS).

    Soojung Park, Yongwon Cho, Yu-Whan Oh, Minseok Ko, Do-Sun Lim in European Radiology (2023)

  6. Article

    Open Access

    Differential clinical impact of chronic total occlusion revascularization based on left ventricular systolic function

    The effect of chronic total occlusion (CTO) revascularization on survival remains controversial. Furthermore, data regarding outcome differences for CTO revascularization based on left ventricular systolic fun...

    Hyungdon Kook, Jeong Hoon Yang, Jae Young Cho in Clinical Research in Cardiology (2021)

  7. Article

    Open Access

    Impact of genetic variants on major bleeding after percutaneous coronary intervention based on a prospective multicenter registry

    Although dual antiplatelet therapy is essential for patients who undergo percutaneous coronary interventions, the risk of bleeding remains an unsolved problem, and there is limited information on the potential...

    Jung-Joon Cha, Hyung Joon Joo, Jae Hyoung Park, Soon Jun Hong in Scientific Reports (2021)

  8. Article

    Open Access

    Identification of plaque ruptures using a novel discriminative model comprising biomarkers in patients with acute coronary syndrome

    Soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1), neutrophil gelatinase-associated lipocalin (NGAL), and matrix metalloproteinase-9 (MMP-9) are inflammatory biomarkers involved in plaqu...

    Hyungdon Kook, Duck Hyun Jang, Jong-Ho Kim, Jae-Young Cho in Scientific Reports (2020)

  9. Article

    Open Access

    Transmural difference in myocardial damage assessed by layer-specific strain analysis in patients with ST elevation myocardial infarction

    We performed layer-specific strain analysis with speckle-tracking echocardiography to investigate the transmural difference of myocardial damage as the predicting factor for the viability of damaged myocardium...

    Sua Kim, Dong-Hyuk Cho, Mi-Na Kim, Soon-Jun Hong, Cheol Woong Yu in Scientific Reports (2020)

  10. Article

    Open Access

    A comparison of procedural success rate and long-term clinical outcomes between in-stent restenosis chronic total occlusion and de novo chronic total occlusion using multicenter registry data

    There have been little data about outcomes of percutaneous coronary intervention (PCI) for in-stent restenosis (ISR) chronic total occlusion (CTO) in the drug eluting stent (DES) era. This study aimed to compa...

    Seung Hun Lee, Jae Young Cho, Je Sang Kim, Hyun Jong Lee in Clinical Research in Cardiology (2020)

  11. Article

    Open Access

    A comparison between drug-eluting stent implantation and drug-coated balloon angioplasty in patients with left main bifurcation in-stent restenotic lesions

    The current guidelines recommend both repeat stenting and drug-coated balloons (DCB) for in-stent restenosis (ISR) lesions, if technically feasible. However, real-world clinical data on the interventional stra...

    Hyungdon Kook, Hyung Joon Joo, Jae Hyoung Park in BMC Cardiovascular Disorders (2020)

  12. Article

    Open Access

    Cardioprotective effects of genetically engineered cardiac stem cells by spheroid formation on ischemic cardiomyocytes

    Sca-1+ cardiac stem cells and their limited proliferative potential were major limiting factors for use in various studies.

    Han Saem Jeong, Chi-Yeon Park, Jong-Ho Kim, Hyung Joon Joo in Molecular Medicine (2020)

  13. Article

    Open Access

    Incidence of new-onset diabetes with 1 mg versus 4 mg pitavastatin in patients at high risk of develo** diabetes during a 3-year follow-up

    Statin therapy reduces the risk of cardiovascular events across a broad spectrum of patients; however, it increases the risk of new-onset diabetes (NOD). Although the highest dose pitavastatin is considered to...

    Han Saem Jeong, Soon Jun Hong, Serhim Son, Hyonggin An in Cardiovascular Diabetology (2019)

  14. No Access

    Article

    The clinical impact of sex differences on ischemic postconditioning during primary percutaneous coronary intervention: a POST (the effects of postconditioning on myocardial reperfusion in patients with ST-segment elevation myocardial infarction) substudy

    The POST (the effects of postconditioning on myocardial reperfusion in patients with ST-Segment elevation myocardial infarction) study showed that ischemic postconditioning did not improve myocardial reperfusi...

    Eun-Seok Shin, Ju-Hyun Chung, Joo-Yong Hahn, Young Bin Song in Heart and Vessels (2019)

  15. Article

    Open Access

    Association between epicardial adipose tissue, high-sensitivity C-reactive protein and myocardial dysfunction in middle-aged men with suspected metabolic syndrome

    As body fat composition and metabolism differ between men and women, we evaluated sex-related differences in the association among epicardial adipose tissue (EAT), secretome profile, and myocardial function of...

    Dong-Hyuk Cho, Hyung Joon Joo, Mi-Na Kim, Do-Sun Lim in Cardiovascular Diabetology (2018)

  16. Article

    Open Access

    Effects of genetic variants on platelet reactivity and one-year clinical outcomes after percutaneous coronary intervention: A prospective multicentre registry study

    Clopidogrel is the mainstay for antiplatelet treatment after percutaneous coronary intervention (PCI). The relationship of platelet reactivity and genetic polymorphism with clinical outcomes with newer-generat...

    Hyung Joon Joo, Sung Gyun Ahn, Jae Hyoung Park, Ji Young Park in Scientific Reports (2018)

  17. Article

    Open Access

    Effects of angiotensin receptor blockers on neointimal characteristics in angina patients requiring stent implantation: optical coherence tomography analysis

    Angiotensin receptor blockers (ARBs) are known for its anti-inflammatory and anti-proliferative effects. The aim of the study was to evaluate long-term effects of ARBs on morphologic characteristics of stent r...

    Jae Young Cho, Soon Jun Hong, Do-Sun Lim in BMC Cardiovascular Disorders (2017)

  18. Article

    Open Access

    The Relationship between Pulse Wave Velocity and Coronary Artery Stenosis and Percutaneous Coronary Intervention: a retrospective observational study

    Arterial stiffness has been suggested as a valuable predictor of coronary artery stenosis (CAS). However, little data are available on aortic stiffness and CAS in patients who have previously undergone percuta...

    Hyung Joon Joo, Sang-A Cho, Jae-Young Cho, Jae Hyoung Park in BMC Cardiovascular Disorders (2017)

  19. Article

    Open Access

    Impact of low high-density lipoprotein-cholesterol level on 2-year clinical outcomes after acute myocardial infarction in patients with diabetes mellitus

    It is still unclear whether low high-density lipoprotein cholesterol (HDL-C) affects cardiovascular outcomes after acute myocardial infarction (AMI), especially in patients with diabetes mellitus.

    Hyung Joon Joo, Sang-A Cho, Soon Jun Hong, Seung-Ho Hur in Lipids in Health and Disease (2016)

  20. Article

    Open Access

    Intrinsic FGF2 and FGF5 promotes angiogenesis of human aortic endothelial cells in 3D microfluidic angiogenesis system

    The human body contains different endothelial cell types and differences in their angiogenic potential are poorly understood. We compared the functional angiogenic ability of human aortic endothelial cells (HA...

    Ha-Rim Seo, Hyo Eun Jeong, Hyung Joon Joo, Seung-Cheol Choi in Scientific Reports (2016)

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