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  1. Article

    Open Access

    Towards validation in clinical routine: a comparative analysis of visual MTA ratings versus the automated ratio between inferior lateral ventricle and hippocampal volumes in Alzheimer’s disease diagnosis

    To assess the performance of the inferior lateral ventricle (ILV) to hippocampal (Hip) volume ratio on brain MRI, for Alzheimer’s disease (AD) diagnostics, comparing it to individual automated ILV and hippocam...

    Mandy M. J. Wittens, Gert-Jan Allemeersch, Diana M. Sima in Neuroradiology (2024)

  2. Article

    Open Access

    Semi-automated brain tumor segmentation on multi-parametric MRI using regularized non-negative matrix factorization

    Segmentation of gliomas in multi-parametric (MP-)MR images is challenging due to their heterogeneous nature in terms of size, appearance and location. Manual tumor segmentation is a time-consuming task and cli...

    Nicolas Sauwen, Marjan Acou, Diana M. Sima, Jelle Veraart in BMC Medical Imaging (2017)

  3. No Access

    Chapter

    Use Case I: Imaging Biomarkers in Neurological Disease. Focus on Multiple Sclerosis

    Imaging is widely used for diagnosis and monitoring of neurological diseases. CT scans are routinely acquired in emergency units in patients with traumatic injuries or stroke. PET imaging has gained a strong f...

    Diana M. Sima, Dirk Loeckx, Dirk Smeets, Saurabh Jain in Imaging Biomarkers (2017)