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Article
Open AccessValidation of remote anthropometric measurements in a rural randomized pediatric clinical trial in primary care settings
Rural children are more at risk for childhood obesity but may have difficulty participating in pediatric weight management clinical trials if in-person visits are required. Remote assessment of height and weig...
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Article
Open AccessPlasma extracellular vesicles bearing PD-L1, CD40, CD40L or TNF-RII are significantly reduced after treatment of AIDS-NHL
Emerging evidence shows that tumor cells secrete extracellular vesicles (EVs) that carry bioactive cell surface markers, such as programmed death-ligand 1 (PD-L1), which can modulate immune responses and inhib...
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Article
Open AccessscHaplotyper: haplotype construction and visualization for genetic diagnosis using single cell DNA sequencing data
Haploty** reveals chromosome blocks inherited from parents to in vitro fertilized (IVF) embryos in preimplantation genetic diagnosis (PGD), enabling the observation of the transmission of disease alleles bet...
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Article
Open AccessBiomass-Assisted Reductive Leaching in H2SO4 Medium for the Recovery of Valuable Metals from Spent Mixed-Type Lithium-Ion Batteries
A hydrometallurgical method involving natural biomass waste as reductant was proposed for the treatment of spent mixed-type lithium-ion batteries. Results showed that almost complete dissolution of Li, Ni, Mn ...
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Article
Open AccessSevere Pollution in China Amplified by Atmospheric Moisture
In recent years, severe haze events often occurred in China, causing serious environmental problems. The mechanisms responsible for the haze formation, however, are still not well understood, hindering the for...
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Article
Open AccessRole of P38 MAPK on MMP Activity in Photothrombotic Stroke Mice as Measured using an Ultrafast MMP Activatable Probe
Matrix metalloproteinases (MMPs) exert a dual effect in ischemic stroke and thus represent an ideal target for detection and therapy. However, to date, all clinical trials of MMP inhibitors have failed and alt...
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Article
Open AccessEvaluation of self-assembled HCPT-loaded PEG-b-PLA nanoparticles by comparing with HCPT-loaded PLA nanoparticles
We present a dialysis technique to prepare the 10-hydroxycamptothecin (HCPT)-loaded nanoparticles (NPs) using methoxypolyethylene glycol-poly(d,l-lactide) (PEG-b-PLA) and PLA, respectively. Both HCPT-loaded PEG-b
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Article
Open AccessBoth FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution
Both folic acid (FA)- and methoxypoly(ethylene glycol) (mPEG)-conjugated chitosan nanoparticles (NPs) had been designed for targeted and prolong anticancer drug delivery system. The chitosan NPs were prepared ...
