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  1. Article

    Open Access

    MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours

    MYC is amplified in approximately 15% of breast cancers (BCs) and is associated with poor outcome. c-MYC protein is multi-faceted and participates in many aspects of cellular function and is linked with therapeut...

    Andrew R Green, Mohammed A Aleskandarany, Devika Agarwal… in British Journal of Cancer (2016)

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  2. No Access

    Article

    The prognostic significance of STAT3 in invasive breast cancer: analysis of protein and mRNA expressions in large cohorts

    Signal transducer and activator of transcription (STAT) transcription factors family are involved in diverse cellular biological functions. Reports regarding the prognostic impact of STAT...

    Mohammed A. Aleskandarany, Devika Agarwal… in Breast Cancer Research and Treatment (2016)

  3. No Access

    Article

    Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers

    DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a serine threonine kinase belonging to the PIKK family (phosphoinositide 3-kinase-like-family of protein kinase), is a critical component of the non-h...

    Tarek Abdel-Fatah, Arvind Arora, Devika Agarwal… in Breast Cancer Research and Treatment (2014)

  4. No Access

    Article

    Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy

    Uracil in DNA is an important cause of mutagenesis. SMUG1 is a uracil-DNA glycosylase that removes uracil through base excision repair. SMUG1 also processes radiation-induced oxidative base damage as well as 5...

    Tarek M. A. Abdel-Fatah, Nada Albarakati… in Breast Cancer Research and Treatment (2013)