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Article
Open AccessMild therapeutic hypothermia upregulates the O-GlcNAcylation level of COX10 to alleviate mitochondrial damage induced by myocardial ischemia–reperfusion injury
Mild therapeutic hypothermia (MTH) is an important method for perioperative prevention and treatment of myocardial ischemia–reperfusion injury (MIRI). Modifying mitochondrial proteins after protein translation...
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Article
Exploring a specialized programmed-cell death patterns to predict the prognosis and sensitivity of immunotherapy in cutaneous melanoma via machine learning
The mortality and therapeutic failure in cutaneous melanoma (CM) are mainly caused by wide metastasis and chemotherapy resistance. Meanwhile, immunotherapy is considered a crucial therapy strategy for CM patie...
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Article
Open AccessThe role of NLRP3 inflammasome in aging and age-related diseases
The gradual aging of the global population has led to a surge in age-related diseases, which seriously threaten human health. Researchers are dedicated to understanding and co** with the complexities of agin...
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Article
Open AccessUpregulated PARP1 confers breast cancer resistance to CDK4/6 inhibitors via YB-1 phosphorylation
Cyclic-dependent kinase (CDK) 4/6 kinases, as the critical drivers of the cell cycle, are involved in the tumor progression of various malignancies. Pharmacologic inhibitors of CDK4/6 have shown significant cl...
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Article
Open AccessEffect of sub-pixel multiplexing on the display quality of LED display
In this paper, a theoretical model is presented for the display process of uniformly-arranged virtual-pixel LED displays with RGBG sub-pixel structure cells. Such displays' modulation transfer function (MTF) i...
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Article
Open AccessGenome-wide identification and expression analysis of the AUX/IAA gene family in turnip (Brassica rapa ssp. rapa)
Auxin/indoleacetic acid (AUX/IAA) genes encoding short-lived proteins participate in AUX signaling transduction and play crucial roles in plant growth and development. Although the AUX/IAA gene family has been...
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Article
Small RNA Profiling Reveals a Role of miRNAs in Response to Ralstonia solanacearum Infection in Tomato
Apart from being a major vegetable crop, tomato (Solanum lycopersicum) is an efficient scientific research model. However, it is vulnerable to bacterial wilt (Bw) caused by Ralstonia solanacearum (Rs); the infect...
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Article
Open AccessGene enrichment and co-expression analysis shed light on transcriptional responses to Ralstonia solanacearum in tomato
Tomato (Solanum lycopersicum) is both an important agricultural product and an excellent model system for studying plant-pathogen interactions. It is susceptible to bacterial wilt caused by Ralstonia solanacearum
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Article
Seeing cancer via sonoafterglow
Afterglow luminescence from nanoparticles can be induced by ultrasound and used for the image-guided treatment and monitoring of tumours in mice.
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Article
Open AccessControlled sequential in situ self-assembly and disassembly of a fluorogenic cisplatin prodrug for cancer theranostics
Temporal control of delivery and release of drugs in tumors are important in improving therapeutic outcomes to patients. Here, we report a sequential stimuli-triggered in situ self-assembly and disassembly str...
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Article
Open AccessCopper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies
Copper is a vital mineral, and an optimal amount of copper is required to support normal physiologic processes in various systems, including the cardiovascular system. Over the past few decades, copper-induced...
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Article
Correction to: A flame-retardant densified wood as robust and fire-safe structural material
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Article
A flame-retardant densified wood as robust and fire-safe structural material
Wood is an abundant, sustainable, low-carbon emission engineering material. However, fire safety issues and insufficient mechanical strength limit its applications. Herein, a simple and scalable method is deve...
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Reference Work Entry In depth
Recent Advances in Modeling Gas-Liquid Flows
Gas-liquid flows are commonly encountered in industrial flow systems. In order to adequately capture the distribution and its effect on the local hydrodynamics in vertical gas-liquid flow, this chapter present...
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Article
Effect of ambient wind on the flame retardancy of intumescent coatings
Ambient wind is an important environmental factor in fire safety research. However, little work has been conducted to investigate the effect of ambient wind on the flame retardancy of intumescent fire-retardan...
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Article
Incorporating ε-Polylysine Hydrochloride, Tea Polyphenols, Nisin, and Ascorbic Acid into Edible Coating Solutions: Effect on Quality and Shelf Life of Marinated Eggs
This study aimed to develop and characterize the chitosan-edible coating solution (CS-NH-TC) incorporated with ε-polylysine hydrochloride, tea polyphenols, nisin, and ascorbic acid and then investigate their e...
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Article
Chromosomal fragment deletion in APRR2-repeated locus modulates the dark stem color in Cucurbita pepo
Cp4.1LG15g03420 (CpDsc-1), which encodes a two-component response regulator-like protein (APRR2) in the nucleus, influences dark green stem formation in Cucurbita pepo by regulating the chlorophyll content.
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Article
The Defluorination of SiF4 on Si (1 1 1) Surfaces: a Density Functional Theory Study
In this paper, the defluorination of SiF4 on Si (1 1 1) surface are studied by adopting density functional theory calculation. SiF4 defluorination on Si (1 1 1) surface will undergo a four-step reaction: (1) SiF4
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Article
Diagnosis of Neisseria Gonorrhoeae by Loop-Mediated Isothermal Amplification: Systematic Review and Meta-Analysis
Neisseria gonorrhoeae (gonococci) is the pathogen of gonorrhea. At present, there is no robust statistical analysis targeting the detection accuracy for N.gonorrhoeae of loop-mediated isothermal amplification (LA...
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Article
Anti-Coking Performance of Ethyl Benzene Pyrolysis of Silicon-Based Films Prepared through Plasma-Enhanced Chemical Vapour Deposition
Non-metal thin films have received considerable attention because they can shield Fe and Ni elements from metal catalytic coking. In this study, the SiF4–H2–Ar mixture gas was used as the silicon source to deposi...