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Article
Wettability and corrosion behavior between alkaline slag from sodium smelting of vanadium–titanium magnetite and refractory substrates
The sodium smelting of vanadium–titanium magnetite can achieve the comprehensive utilization of Fe, V, and Ti. However, the generation of alkaline slag during this process may cause damage to refractory materi...
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Article
Open AccessNeoadjuvant chemotherapy followed by surgery versus concurrent chemoradiotherapy in patients with stage IIB cervical squamous cell carcinoma: a retrospective cohort study
This study aims to compare treatment outcomes between neoadjuvant chemotherapy (NACT) followed by surgery and concurrent chemoradiotherapy (CCRT) in patients with stage IIB cervical squamous cell carcinoma (CS...
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Article
Open AccessXELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase 3 trial
Fluoropyrimidine-based combination chemotherapy plus targeted therapy is the standard initial treatment for unresectable metastatic colorectal cancer (mCRC), but the prognosis remains poor. This phase 3 trial ...
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Article
Combined toxic effects of polystyrene nanoplastics and lead on Chlorella vulgaris growth, membrane lipid peroxidation, antioxidant capacity, and morphological alterations
In recent years, there has been a significant rise in the utilization of amino-functionalized polystyrene nanoplastics (PS-NH2). This surge in usage can be attributed to their exceptional characteristics, includi...
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Article
N6-Methyladenosine (m6A) Methylation Is Associated with the Immune Microenvironments in Acute Intracerebral Hemorrhage (ICH)
Researchers have recently found that N6-methyladenosine (m6A) is a type of internal posttranscriptional modification that is essential in mammalian mRNA. However, the features of m6A RNA methylation in acute intr...
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Article
Open AccessLow frequency of SLC26A4 c.919-2A > G variant among patients with nonsyndromic hearing loss in Yunnan of Southwest China
Gene variants are responsible for more than half of hearing loss, particularly in nonsyndromic hearing loss (NSHL). The most common pathogenic variant in SLC26A4 gene found in East Asian populations is c.919-2A >...
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Article
Open AccessEfficacy of treatment patterns based on concurrent chemoradiotherapy in patients with stage IIB cervical squamous cell carcinoma
To assess survival of treatment patterns based on concurrent chemoradiotherapy (CCRT) in patients with stage IIB cervical squamous cell carcinoma (CSCC).
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Article
Open AccessBiogeographic patterns of meio- and micro-eukaryotic communities in dam-induced river-reservoir systems
Although the Three Gorges Dam (TGD) is the world’s largest hydroelectric dam, little is known about the spatial–temporal patterns and community assembly mechanisms of meio- and micro-eukaryotes and its two sub...
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Article
Open AccessAnterior cervical discectomy and fusion with a zero-profile VA spacer device: a clinical and radiological study with two-year follow-up
A retrospective study.
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Chapter and Conference Paper
Experimental Study on Pool Boiling Heat Transfer Characteristics of SiC Cladding Under Atmospheric Pressure
Since the Fukushima accident in Japan, Accident-Tolerant Fuel (ATF) was investigated to mitigate the zircaloy-water oxidation reaction at a high temperature. Silicon carbide (SiC) cladding is one of the most p...
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Chapter and Conference Paper
Research on Optimal Design of Fracture Parameters for Horizontal Wells Multi-Stage Fracturing in Coalbed Methane Reservoirs
Hydraulic fracturing has become a key technology for develo** unconventional coalbed methane reservoirs. Fracture parameters directly affect the fracture propagation patterns and the effect of hydraulic frac...
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Chapter and Conference Paper
Study on Optimization Design of Hydraulic Fracturing Construction Parameters for Vertical Wells in Low-Permeability Reservoirs
The construction parameters of hydraulic fracturing have a direct impact on the propagation morphology of fractures and the post-fracturing productivity of single well. Optimizing the construction parameters c...
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Chapter and Conference Paper
Research on Bottom Water Coning Law of Jurassic Reservoir–Based on Kv/Kh Value Recognition
The ratio of vertical permeability (Kv) to horizontal permeability (Kh) of a reservoir (Kv/Kh) is crucial for studying the bottom water coning law of bottom water reservoirs, understanding the characteristics of ...
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Chapter and Conference Paper
Physical Simulation Study on Horizontal Well Injection and Production in Ultra-low Permeability Reservoirs
In order to study the displacement mechanism between horizontal well fractures, seepage law, and the impact of horizontal well renovation parameters on development effectiveness, a large-scale outcrop rock sam...
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Article
Open AccessCorrection: Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K/AKT/GSK3β signalling pathway in renal cell carcinoma
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Article
Open AccessStructural and functional analyses of Burkholderia pseudomallei BPSL1038 reveal a Cas-2/VapD nuclease sub-family
Burkholderia pseudomallei is a highly versatile pathogen with ~25% of its genome annotated to encode hypothetical proteins. One such hypothetical protein, BPSL1038, is conserved across seven bacterial genera and ...
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Article
Open AccessA new glance at autophagolysosomal-dependent or -independent function of transcriptional factor EB in human cancer
Autophagy-lysosome system plays a variety of roles in human cancers. In addition to being implicated in metabolism, it is also involved in tumor immunity, remodeling the tumor microenvironment, vascular prolif...
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Article
Numerical investigations on performance improvement mechanism of a high-power vertical centrifugal pump with special emphasis on hydraulic component matching
The purpose of this paper is to investigate the performance improvement mechanism of a high power vertical centrifugal pump by using numerical calculations. Therefore, a comparative study of energy losses and ...
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Article
Biofabricated gold nanoparticles from Ammannia baccifera as potential antimicrobial, mosquito larvicidal activity, and alter immune response in zebrafish embryo
Gold nanoparticles (GNPs) are commonly utilized in biomedical science, but the potential application of green synthesized herb-based GNPs is elusive. Here, aqueous extracts of Ammannia baccifera were used to synt...
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Article
Open AccessHernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway
Hernandezine (Her) is a bisbenzylisoquinoline alkaloid extracted from the traditional Chinese herbal medicine Thalictrum glandulosissimum. Evidence shows that Her is a natural agonist of adenosine monophosphate (...
