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Article
Open AccessGenome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes
Excessive daytime sleepiness (EDS) affects 10–20% of the population and is associated with substantial functional deficits. Here, we identify 42 loci for self-reported daytime sleepiness in GWAS of 452,071 ind...
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Article
Open AccessThe circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication
The circadian clock regulates immune responses to microbes and affects pathogen replication, but the underlying molecular mechanisms are not well understood. Here we demonstrate that the circadian components B...
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Article
Open AccessA non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response
The glucocorticoid receptor (GR) is essential for the stress response in mammals. We investigated potential non-transcriptional roles of GR in cellular stress response using fission yeast as a model.We surpris...