Skip to main content

and
  1. Article

    Open Access

    Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes

    Excessive daytime sleepiness (EDS) affects 10–20% of the population and is associated with substantial functional deficits. Here, we identify 42 loci for self-reported daytime sleepiness in GWAS of 452,071 ind...

    Heming Wang, Jacqueline M. Lane, Samuel E. Jones, Hassan S. Dashti in Nature Communications (2019)

  2. Article

    Open Access

    The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication

    The circadian clock regulates immune responses to microbes and affects pathogen replication, but the underlying molecular mechanisms are not well understood. Here we demonstrate that the circadian components B...

    **aodong Zhuang, Andrea Magri, Michelle Hill, Alvina G. Lai in Nature Communications (2019)

  3. Article

    Open Access

    A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response

    The glucocorticoid receptor (GR) is essential for the stress response in mammals. We investigated potential non-transcriptional roles of GR in cellular stress response using fission yeast as a model.We surpris...

    Marina Ptushkina, Toryn Poolman, Mudassar Iqbal, Mark Ashe in Scientific Reports (2017)