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  1. Article

    Open Access

    Context-specific emergence and growth of the SARS-CoV-2 Delta variant

    The SARS-CoV-2 Delta (Pango lineage B.1.617.2) variant of concern spread globally, causing resurgences of COVID-19 worldwide1,2. The emergence of the Delta variant in the UK occurred on the background of a hetero...

    John T. McCrone, Verity Hill, Sumali Bajaj, Rosario Evans Pena, Ben C. Lambert in Nature (2022)

  2. Article

    Open Access

    A global resource for genomic predictions of antimicrobial resistance and surveillance of Salmonella Typhi at pathogenwatch

    As whole-genome sequencing capacity becomes increasingly decentralized, there is a growing opportunity for collaboration and the sharing of surveillance data within and between countries to inform typhoid cont...

    Silvia Argimón, Corin A. Yeats, Richard J. Goater, Khalil Abudahab in Nature Communications (2021)

  3. Article

    Open Access

    Integrating whole-genome sequencing within the National Antimicrobial Resistance Surveillance Program in the Philippines

    National networks of laboratory-based surveillance of antimicrobial resistance (AMR) monitor resistance trends and disseminate these data to AMR stakeholders. Whole-genome sequencing (WGS) can support surveill...

    Silvia Argimón, Melissa A. L. Masim, June M. Gayeta in Nature Communications (2020)

  4. Article

    Open Access

    The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa

    There is paucity of data regarding the geographical distribution, incidence, and phylogenetics of multi-drug resistant (MDR) Salmonella Typhi in sub-Saharan Africa. Here we present a phylogenetic reconstruction o...

    Se Eun Park, Duy Thanh Pham, Christine Boinett, Vanessa K. Wong in Nature Communications (2018)

  5. Article

    Open Access

    Development and worldwide use of non-lethal, and minimal population-level impact, protocols for the isolation of amphibian chytrid fungi

    Parasitic chytrid fungi have emerged as a significant threat to amphibian species worldwide, necessitating the development of techniques to isolate these pathogens into culture for research purposes. However, ...

    Matthew C. Fisher, Pria Ghosh, Jennifer M. G. Shelton, Kieran Bates in Scientific Reports (2018)

  6. Article

    Open Access

    Emergence and clonal spread of colistin resistance due to multiple mutational mechanisms in carbapenemase-producing Klebsiella pneumoniae in London

    Carbapenemase-producing Enterobacteriaceae (CPE) are emerging worldwide, limiting therapeutic options. Mutational and plasmid-mediated mechanisms of colistin resistance have both been reported. The emergence a...

    Jonathan A. Otter, Michel Doumith, Frances Davies in Scientific Reports (2017)

  7. Article

    Open Access

    Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection

    Schistosoma mansoni is a parasitic fluke that infects millions of people in the develo** world. This study presents the first application of population genomics to S. mansoni based on high-coverage resequencing...

    Thomas Crellen, Fiona Allan, Sophia David, Caroline Durrant in Scientific Reports (2016)