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Article
Open AccessPrediction of pathological complete response and prognosis in patients with neoadjuvant treatment for triple-negative breast cancer
It has been reported that pathological complete response is an important surrogate marker for disease-free survival and overall survival in patients with triple-negative breast cancer. This study investigates ...
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Article
Open AccessDNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer
Identifying molecular alterations in normal tissue adjacent to cancer is important for understanding cancer aetiology and designing preventive measures. Here we analyse the DNA methylome of 569 breast tissue s...
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Article
Open AccessFine needle aspiration cytology of lymph nodes in breast cancer follow-up is a feasible alternative to watchful waiting and to histology
Early detection of loco-regional breast cancer recurrence improves patients’ overall survival, as treatment can be initiated or active treatment can be changed. If a suspicious lymph node is diagnosed during a...
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Article
Open AccessOncofertility: combination of ovarian stimulation with subsequent ovarian tissue extraction on the day of oocyte retrieval
New anticancer treatments have increased survival rates for cancer patients, but often at the cost of sterility. Several strategies are currently available for preserving fertility. However, the chances of ach...
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Article
Open AccessKi67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment
The pathological complete response (pCR) after neoadjuvant chemotherapy is a surrogate marker for a favorable prognosis in breast cancer patients. Factors capable of predicting a pCR, such as the proliferation...
