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  1. Article

    Open Access

    Towards a structurally resolved human protein interaction network

    Cellular functions are governed by molecular machines that assemble through protein-protein interactions. Their atomic details are critical to studying their molecular mechanisms. However, fewer than 5% of hun...

    David F. Burke, Patrick Bryant in Nature Structural & Molecular Biology (2023)

  2. Article

    Open Access

    Comparative modelling by restraint-based conformational sampling

    Although comparative modelling is routinely used to produce three-dimensional models of proteins, very few automated approaches are formulated in a way that allows inclusion of restraints derived from experime...

    Nicholas Furnham, Paul IW de Bakker, Swanand Gore, David F Burke in BMC Structural Biology (2008)