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  1. Article

    Open Access

    Age-related increase in live-birth rates of first frozen thaw embryo versus first fresh transfer in initial assisted reproductive technology cycles without PGT

    The landscape of assisted reproductive technology (ART) has seen a significant shift towards frozen-thawed embryo transfers (FET) over fresh transfers, driven by technological advancements and clinical conside...

    Sarah F Wang, David B Seifer in Reproductive Biology and Endocrinology (2024)

  2. Article

    Open Access

    A modern-day litmus test for the sustainability of daily IVF practice - Alabama supreme court ruling overreaches in asserting that frozen embryos are legally children

    David B. Seifer in Reproductive Biology and Endocrinology (2024)

  3. Article

    Open Access

    Cumulative live birth rates with autologous oocytes plateau with fewer number of cycles for each year of age > 42

    To disaggregate the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) age category of “ > 42” and compare age-stratified cumulative live birth rates (CLBR) > 42 years old.

    David B. Seifer, Sarah F. Wang, David Frankfurter in Reproductive Biology and Endocrinology (2023)

  4. Article

    Open Access

    Women with PCOS who undergo IVF: a comprehensive review of therapeutic strategies for successful outcomes

    Polycystic ovarian syndrome (PCOS) is a widespread syndrome that poses unique challenges and constraints to the field of assisted reproductive technology. This condition is the most common cause of anovulation...

    Alexander M. Kotlyar, David B. Seifer in Reproductive Biology and Endocrinology (2023)

  5. Article

    Open Access

    AMH predicts miscarriage in non-PCOS but not in PCOS related infertility ART cycles

    To study whether AMH levels were associated with miscarriage rates in index ART cycles undergoing fresh autologous transfers in PCOS and non-PCOS related infertility.

    Christopher Arkfeld, Eric Han, Reshef Tal in Reproductive Biology and Endocrinology (2023)

  6. Article

    Open Access

    AMH independently predicts aneuploidy but not live birth per transfer in IVF PGT-A cycles

    While anti-Müllerian hormone (AMH) predicts quantitative IVF outcomes such as oocyte yield, it is not certain whether AMH predicts markers of oocyte quality such as aneuploidy.

    Howard J. Li, David B. Seifer, Reshef Tal in Reproductive Biology and Endocrinology (2023)

  7. Article

    Open Access

    Age-related changes in Folliculogenesis and potential modifiers to improve fertility outcomes - A narrative review

    Reproductive aging is characterized by a decline in oocyte quantity and quality, which is directly associated with a decline in reproductive potential, as well as poorer reproductive success and obstetrical ou...

    Ecem Esencan, Gabriela Beroukhim, David B. Seifer in Reproductive Biology and Endocrinology (2022)

  8. No Access

    Article

    SART CORS IVF registry: looking to the past to shape future perspectives

    The SART CORS database is an informative source of IVF clinic-specific linked data that provides cumulative live birth rates from medically assisted reproduction in the United States (US). These data are used ...

    Carol Lynn Curchoe, Oishika Tarafdar in Journal of Assisted Reproduction and Genet… (2022)

  9. Article

    Open Access

    Impact of in vitro fertilization state mandates for third party insurance coverage in the United States: a review and critical assessment

    The American Society for Reproductive Medicine estimates that fewer than a quarter of infertile couples have sufficient access to infertility care. Insurers in the United States (US) have long considered infer...

    Benjamin J. Peipert, Melissa N. Montoya in Reproductive Biology and Endocrinology (2022)

  10. No Access

    Article

    The Disparities in ART (DART) Hypothesis of Racial and Ethnic Disparities in Access and Outcomes of IVF Treatment in the USA

    We propose the Disparities in ART (DART) hypothesis which identifies underlining causes that contribute to racial disparities in access and outcomes of ART treatment in the USA. Reasons for disparities in acce...

    David B. Seifer, Fady I. Sharara, Tarun Jain in Reproductive Sciences (2022)

  11. Article

    Open Access

    Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review

    Sleep is vital to human bodily function. Growing evidence indicates that sleep deprivation, disruption, dysrhythmia, and disorders are associated with impaired reproductive function and poor clinical outcomes ...

    Gabriela Beroukhim, Ecem Esencan, David B. Seifer in Reproductive Biology and Endocrinology (2022)

  12. Article

    Open Access

    Preeclampsia at delivery is associated with lower serum vitamin D and higher antiangiogenic factors: a case control study

    Preeclampsia is characterized by decreased trophoblastic angiogenesis leading to abnormal invasion of spiral arteries, shallow implantation and resulting in compromised placentation with poor uteroplacental pe...

    David B. Seifer, Geralyn Lambert-Messerlian in Reproductive Biology and Endocrinology (2022)

  13. No Access

    Chapter

    Emerging Concepts: Role of Vitamin D Deficiency in the Pathogenesis of PCOS

    Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. The metabolic milieu of PCOS puts this population at enhanced lifetime risk for a spectrum of morbidities includ...

    Samantha Simpson, Lubna Pal, David B. Seifer in Polycystic Ovary Syndrome (2022)

  14. No Access

    Chapter

    The Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome

    Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder that affects up to 10% of reproductive age women. It is characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. Ovar...

    Alice Y. Chen, David B. Seifer, Reshef Tal in Polycystic Ovary Syndrome (2022)

  15. No Access

    Chapter

    Anti-Mullerian Hormone Signaling: Relevance for Pathophysiology of PCOS and Implications for Novel Therapeutic Approaches to Managing Ovulatory Dysfunction of PCOS

    Anti-Mullerian hormone (AMH) is often elevated in patients with polycystic ovary syndrome (PCOS). There is increasing evidence that high serum AMH is not only a marker of the disorder but plays a critical role...

    Alice J. Shapiro, Vitaly Kushnir, David B. Seifer in Polycystic Ovary Syndrome (2022)

  16. Article

    Open Access

    Differences in ICSI utilization rates among states with insurance mandates for ART coverage

    Assisted reproductive technology (ART) insurance mandates promote more selective utilization of ART clinic resources including intracytoplasmic sperm injection (ICSI). Our objective was to examine whether ICSI...

    Pavel Zagadailov, Kyung S. Cho, David B. Seifer in Reproductive Biology and Endocrinology (2021)

  17. Article

    Open Access

    Correction to: Status of racial disparities between black and white women undergoing assisted reproductive technology in the US

    David B. Seifer, Burcin Simsek, Ethan Wantman in Reproductive Biology and Endocrinology (2021)

  18. Article

    Open Access

    Correction to: Psychological experience and co** strategies of patients in the Northeast US delaying care for infertility during the COVID-19 pandemic

    An amendment to this paper has been published and can be accessed via the original article.

    David B. Seifer, William D. Petok, Alisha Agrawal in Reproductive Biology and Endocrinology (2021)

  19. Article

    Open Access

    Psychological experience and co** strategies of patients in the Northeast US delaying care for infertility during the COVID-19 pandemic

    On March 17, 2020 an expert ASRM task force recommended the temporary suspension of new, non-urgent fertility treatments during an ongoing world-wide pandemic of Covid-19. We surveyed at the time of resumption...

    David B. Seifer, William D. Petok, Alisha Agrawal in Reproductive Biology and Endocrinology (2021)

  20. Article

    Open Access

    Correction to: Status of racial disparities between black and white women undergoing assisted reproductive technology in the US

    An amendment to this paper has been published and can be accessed via the original article.

    David B. Seifer, Burcin Simsek, Ethan Wantman in Reproductive Biology and Endocrinology (2020)

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