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within David B. Darr Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

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  1. Article

    Open Access

    cMET inhibitor crizotinib impairs angiogenesis and reduces tumor burden in the C3(1)-Tag model of basal-like breast cancer

    Epidemiologic studies have associated obesity with increased risk of the aggressive basal-like breast cancer (BBC) subtype. Hepatocyte growth factor (HGF) signaling through its receptor, cMET, is elevated in o...

    Alyssa J. Cozzo, Sneha Sundaram, Ottavia Zattra, Yuanyuan Qin… in SpringerPlus (2016)

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  2. No Access

    Article

    Coexistent ARID1A–PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling

    Ovarian clear-cell carcinoma (OCCC) is an aggressive form of ovarian cancer with high ARID1A mutation rates. Here we present a mutant mouse model of OCCC. We find that ARID1A inactivation is not sufficient for tu...

    Ronald L. Chandler, Jeffrey S. Damrauer, Jesse R. Raab… in Nature Communications (2015)