3 Result(s)
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Article
Open AccessChromosomally normal miscarriage is associated with vaginal dysbiosis and local inflammation
Emerging evidence supports an association between vaginal microbiota composition and risk of miscarriage; however, the underlying mechanisms are poorly understood. We aim to investigate the vaginal microbial c...
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Article
Open AccessVaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin
Preterm prelabour rupture of the fetal membranes (PPROM) precedes 30% of preterm births and is a risk factor for early onset neonatal sepsis. As PPROM is strongly associated with ascending vaginal infection, p...
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Article
Open AccessModeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomics
Preterm birth is now recognized as the primary cause of infant mortality worldwide. Interplay between hormonal and inflammatory signaling in the uterus modulates the onset of contractions; however, the relativ...
