7 Result(s)
within
David A. Flockhart
Biomedicine
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Article
Open AccessThe IGNITE network: a model for genomic medicine implementation and research
Patients, clinicians, researchers and payers are seeking to understand the value of using genomic information (as reflected by genoty**, sequencing, family history or other data) to inform clinical decision-...
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Article
Pharmacogenetics and healthcare outcomes in patients with chronic heart failure
To test for associations between genetic polymorphisms of adrenergic receptors (AR) and other candidate genes and healthcare utilization in heart failure patients, taking into account other important factors, ...
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Article
Creating and evaluating genetic tests predictive of drug response
Recent advances in genomic knowledge and associated technologies should help accelerate the development of genetic tests that can predict drug response and toxicity; however several challenges remain. Here, We...
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Article
Breast cancer treatment and ovarian failure: risk factors and emerging genetic determinants
Most premenopausal women diagnosed with primary breast cancer receive adjuvant chemotherapy, and many experience chemotherapy-induced ovarian failure (CIOF). Can inherited genetic factors and a better understa...
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Article
CYP2D6 genotype and tamoxifen response
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Article
Creating incentives for genomic research to improve targeting of therapies
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Article
Teaching rational prescribing: a new clinical pharmacology curriculum for medical schools
In most U.S. and Canadian medical schools, pharmacology is taught during the preclinical year 2 of the 4-year-long curriculum. This is despite the fact that medical school graduates and residency directors ha...
