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  1. No Access

    Article

    Large Stokes shift fluorescent RNAs for dual-emission fluorescence and bioluminescence imaging in live cells

    Fluorescent RNAs, aptamers that bind and activate small fluorogenic dyes, have provided a particularly attractive approach to visualizing RNAs in live cells. However, the simultaneous imaging of multiple RNAs ...

    Li Jiang, **n **e, Ni Su, Dasheng Zhang, **anjun Chen, **aochen Xu… in Nature Methods (2023)

  2. Article

    Open Access

    Design of a palette of SNAP-tag mimics of fluorescent proteins and their use as cell reporters

    Naturally occurring fluorescent proteins (FPs) are the most widely used tools for tracking cellular proteins and sensing cellular events. Here, we chemically evolved the self-labeling SNAP-tag into a palette o...

    Dasheng Zhang, Zhengda Chen, Zengmin Du, Bingkun Bao, Ni Su, **anjun Chen… in Cell Discovery (2023)

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  3. No Access

    Article

    Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs

    Fluorescent RNAs (FRs), aptamers that bind and activate fluorescent dyes, have been used to image abundant cellular RNA species. However, limitations such as low brightness and limited availability of dye/apta...

    **anjun Chen, Dasheng Zhang, Ni Su, Bingkun Bao, **n **e… in Nature Biotechnology (2019)

  4. Article

    Tom70 serves as a molecular switch to determine pathological cardiac hypertrophy

    Pathological cardiac hypertrophy is an inevitable forerunner of heart failure. Regardless of the etiology of cardiac hypertrophy, cardiomyocyte mitochondrial alterations are always observed in this context. Th...

    Jun Li, Man Qi, Changming Li, Dan Shi, Dasheng Zhang, Duanyang **e… in Cell Research (2014)

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