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    Open Access

    Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo

    Intervertebral disc degeneration (IDD) is a complicated process that involves both cellular apoptosis and senescence. Metformin has been reported to stimulate autophagy, whereas autophagy is shown to protect a...

    Deheng Chen, Dongdong **a, Zongyou Pan, Daoliang Xu, Yifei Zhou in Cell Death & Disease (2016)