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  1. Article

    Open Access

    A Fragment of Collagen Type VI alpha-3 chain is Elevated in Serum from Patients with Gastrointestinal Disorders

    Extracellular matrix (ECM) remodeling is a hallmark of the pathology of gastrointestinal disorders. Collagen type VI (COL6) is produced by fibroblasts, and the COL6 α3-chain has shown to be elevated in patient...

    Signe Holm Nielsen, Joachim Høg Mortensen, Nicholas Willumsen in Scientific Reports (2020)

  2. Article

    Open Access

    Collagen turnover profiles in chronic kidney disease

    Renal fibrosis is a hallmark of chronic kidney disease (CKD) caused by an imbalance between formation and degradation of extracellular matrix proteins. We investigated the collagen turnover profile of 81 non-d...

    Daniel Guldager Kring Rasmussen, Lene Boesby, Signe Holm Nielsen in Scientific Reports (2019)

  3. Article

    Open Access

    Urinary endotrophin predicts disease progression in patients with chronic kidney disease

    Renal fibrosis is the central pathogenic process in progression of chronic kidney disease (CKD). Collagen type VI (COL VI) is upregulated in renal fibrosis. Endotrophin is released from COL VI and promotes ple...

    Daniel Guldager Kring Rasmussen, Anthony Fenton, Mark Jesky in Scientific Reports (2017)