12 Result(s)
within
Daniel A Leongamornlert
-
Article
Open AccessCorrection: Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease
This article was originally published under the standard License to Publish, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the paper have been modified accordingly.
-
Article
Open AccessRare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease
Prostate cancer (PrCa) demonstrates a heterogeneous clinical presentation ranging from largely indolent to lethal. We sought to identify a signature of rare inherited variants that distinguishes between these ...
-
Article
Open AccessFine-map** of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian multivariate ...
-
Article
Open AccessErratum: Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genoty** array
Correction to: British Journal of Cancer (2016) 114, 945–952. doi:10.1038/bjc.2016.50; published online 10 March 2016 Following the publication of this manuscript, it was recognised that some of the names incl...
-
Article
Open AccessErratum: Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition
Correction to: British Journal of Cancer (2018) 118, 266–276; doi:10.1038/bjc.2017.429; published online 04 January 2018 The authors would like to acknowledge the following information for this manuscript: Chr...
-
Article
Open AccessProstate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition
Prostate-specific antigen (PSA) and PSA-velocity (PSAV) have been used to identify men at risk of prostate cancer (PrCa). The IMPACT study is evaluating PSA screening in men with a known genetic predisposition...
-
Article
Open AccessGene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genoty** array
Germline mutations within DNA-repair genes are implicated in susceptibility to multiple forms of cancer. For prostate cancer (PrCa), rare mutations in BRCA2 and BRCA1 give rise to moderately elevated risk, wherea...
-
Article
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genoty** array
Rosalind Eeles and colleagues report meta-analysis of genome-wide association studies for prostate cancer and genoty** on the custom iCOGS array in 25,074 cases and 24,272 controls from 32 studies available ...
-
Article
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study
Rosalind Eeles and colleagues report a multistage genome-wide association study of prostate cancer, identifying seven new prostate cancer susceptibility loci.
-
Article
Multiple loci on 8q24 associated with prostate cancer susceptibility
Douglas Easton and colleagues report a comprehensive analysis of SNP associations to prostate cancer across the 8q24 region. They report 8 SNPs in 5 blocks independently associated to prostate cancer risk.
-
Article
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
Rosalind Eeles and colleagues present a genome-wide association study for prostate cancer. They report seven loci newly associated with prostate cancer susceptibility.
-
Article
Multiple newly identified loci associated with prostate cancer susceptibility
Prostate cancer is the most common cancer affecting males in developed countries. It shows consistent evidence of familial aggregation, but the causes of this aggregation are mostly unknown. To identify common...
