18 Result(s)
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Dandan Zheng
Biomedicine
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Article
Hsa_circ_0007590/PTBP1 complex reprograms glucose metabolism by reducing the stability of m6A-modified PTEN mRNA in pancreatic ductal adenocarcinoma
The role of circular RNAs (circRNAs) in glucose metabolism in pancreatic duct adenocarcinoma (PDAC) remains elusive. Through RNA sequencing of cells cultured under conditions of glucose deprivation, we identif...
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Article
Open AccessDosimetric evaluation of LINAC-based single-isocenter multi-target multi-fraction stereotactic radiosurgery with more than 20 targets: comparing MME, HyperArc, and RapidArc
To compare the dosimetric quality of three widely used techniques for LINAC-based single-isocenter multi-target multi-fraction stereotactic radiosurgery (fSRS) with more than 20 targets: dynamic conformal arc ...
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Article
Open AccessTargeting MYH9 represses USP14-mediated NAP1L1 deubiquitination and cell proliferation in glioma
Myosin heavy chain 9 (MYH9) plays an important role in a number of diseases. Nevertheless, the function of MYH9 in glioma is unclear. The present research aimed to investigate the role of MYH9 in glioma and de...
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Article
Biallelic CLCN2 mutations cause retinal degeneration by impairing retinal pigment epithelium phagocytosis and chloride channel function
CLCN2 encodes a two-pore homodimeric chloride channel protein (CLC-2) that is widely expressed in human tissues. The association between Clcn2 and the retina is well-established in mice, as loss-of-function of CL...
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Protocol
B-Cell Epitope Predictions Using Computational Methods
Identifying protein antigenic epitopes that are recognizable by antibodies is a key step in immunologic research. This type of research has broad medical applications, such as new immunodiagnostic reagent disc...
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Article
Open AccessActivation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin-9
Colorectal cancer (CRC) is a common tumor characterized by its high mortality. However, the underlying molecular mechanisms that drive CRC tumorigenesis are unclear. Clock genes have important roles in tumor d...
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Article
Open AccessCorrection to: Correlation of dosimetric factors with the development of symptomatic radiation pneumonitis in stereotactic body radiotherapy
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessCorrection to: The structure–activity relationship review of the main bioactive constituents of Morus genus plants
The article The structure–activity relationship review of the main bioactive constituents of Morus genus plants, written by Jie**g Yan, **gya Ruan, Peijian Huang, Fan Sun, Dandan Zheng, Yi Zhang and Tao Wang wa...
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Article
Open AccessThe structure–activity relationship review of the main bioactive constituents of Morus genus plants
Morus genus plants are mainly distributed in the temperate to tropical areas over the world and include 17 species and two subspecies. Due to their excellent pharmacological activity, security in food additives a...
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Article
Open AccessDosimetric consequences of image guidance techniques on robust optimized intensity-modulated proton therapy for treatment of breast Cancer
To investigate the consequences of residual setup error on target dose distribution using various image registration strategies for breast cancer treated with intensity-modulated proton therapy (IMPT).
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Article
Open AccessCorrelation of dosimetric factors with the development of symptomatic radiation pneumonitis in stereotactic body radiotherapy
The development of radiation pneumonitis (RP) after Stereotactic Body Radiotherapy (SBRT) is known to be associated with many different factors, although historical analyses of RP have commonly utilized hetero...
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Protocol
EPCES and EPSVR: Prediction of B-Cell Antigenic Epitopes on Protein Surfaces with Conformational Information
Accurate prediction of discontinuous antigenic epitopes is important for immunologic research and medical applications, but it is not an easy problem. Currently, there are only a few prediction servers availab...
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Protocol
SVMTriP: A Method to Predict B-Cell Linear Antigenic Epitopes
Identifying protein antigenic epitopes recognizable by antibodies is the key step for new immuno-diagnostic reagent discovery and vaccine design. To facilitate this process and improve its efficiency, computat...
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Article
Open AccessComparative analysis of rodent and small mammal viromes to better understand the wildlife origin of emerging infectious diseases
Rodents represent around 43% of all mammalian species, are widely distributed, and are the natural reservoirs of a diverse group of zoonotic viruses, including hantaviruses, Lassa viruses, and tick-borne encep...
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Article
Open AccessPrognostic factors of radiation dermatitis following passive-scattering proton therapy for breast cancer
To identify prognostic factors for grade 3 radiation dermatitis following passive-scattering proton therapy for breast cancer.
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Article
Open AccessA comprehensive dosimetric study on switching from a Type-B to a Type-C dose algorithm for modern lung SBRT
Type-C dose algorithms provide more accurate dosimetry for lung SBRT treatment planning. However, because current dosimetric protocols were developed based on conventional algorithms, its applicability for the...
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Article
Open AccessTarget dose conversion modeling from pencil beam (PB) to Monte Carlo (MC) for lung SBRT
A challenge preventing routine clinical implementation of Monte Carlo (MC)-based lung SBRT is the difficulty of reinterpreting historical outcome data calculated with inaccurate dose algorithms, because the ta...
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Article
Open AccessA heterozygous moth genome provides insights into herbivory and detoxification
Minsheng You and colleagues report the whole-genome sequence of the diamondback moth, Plutella xylostella. Their transcriptome analysis from different life stages, together with comparative genomic and phylogenet...
