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within Medicine & Public Health Remove this filter Medicine/Public Health, general Remove this filter Dan T. Vogl Remove this filter

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  1. Article

    Open Access

    Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials

    Selinexor is an oral, small molecule inhibitor of the nuclear export protein exportin 1 with demonstrated activity in hematologic and solid malignancies. Side effects associated with selinexor include nausea, ...

    Maria Gavriatopoulou, Ajai Chari, Christine Chen, Nizar Bahlis, Dan T. Vogl… in Leukemia (2020)

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  2. Article

    Open Access

    RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation

    Ikaros family zinc finger protein 1 and 3 (IKZF1 and IKZF3) are transcription factors that promote multiple myeloma (MM) proliferation. The immunomodulatory imide drug (IMiD) lenalidomide promotes myeloma cell...

    Nan Zhou, Alvaro Gutierrez-Uzquiza, **ang Yu Zheng, Renxu Chang, Dan T. Vogl… in Leukemia (2019)

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