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  1. No Access

    Article

    The regulation of necroptosis by ubiquitylation

    Necroptosis is a programmed necrosis that is mediated by receptor-interacting protein kinases RIPK1, RIPK3 and the mixed lineage kinase domain-like protein, MLKL. Necroptosis must be strictly regulated to main...

    Yiliang Chen, Wenqing Ren, Qingsong Wang, Yuan He, Dan Ma, Zhenyu Cai in Apoptosis (2022)

  2. Article

    Open Access

    Correction to: Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma

    An amendment to this paper has been published and can be accessed via the original article.

    Yan Chen, Zhonghu Li, Mengyun Zhang, Bo Wang in Journal of Experimental & Clinical Cancer … (2021)

  3. Article

    Open Access

    m6A-dependent glycolysis enhances colorectal cancer progression

    Epigenetic alterations are involved in various aspects of colorectal carcinogenesis. N6-methyladenosine (m6A) modifications of RNAs are emerging as a new layer of epigenetic regulation. As the most abundant chemi...

    Chaoqin Shen, Baoqin Xuan, Tingting Yan, Yanru Ma, **** Xu in Molecular Cancer (2020)

  4. Article

    Open Access

    Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma

    Circular RNAs (circRNAs) have recently been shown to play important roles in different tumors. However, their detailed roles and regulatory mechanisms in pancreatic ductal adenocarcinoma (PDAC) are not well un...

    Yan Chen, Zhonghu Li, Mengyun Zhang, Bo Wang in Journal of Experimental & Clinical Cancer … (2019)

  5. No Access

    Article

    Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility

    Xu Tan, Yong Yang and colleagues identify patients with epidermolysis bullosa harboring mutations in KLHL24, which encodes a cullin 3–RBX1 ubiquitin ligase substrate receptor. They find that truncating mutations ...

    Zhimiao Lin, Shuo Li, Cheng Feng, Shang Yang, Huijun Wang, Danhui Ma in Nature Genetics (2016)

  6. No Access

    Article

    INPP4B-mediated DNA repair pathway confers resistance to chemotherapy in acute myeloid leukemia

    INPP4B has been recently shown to be a poor prognostic marker and confer chemo- or radio-resistance in AML cells, whereas, the underlying mechanisms remain unclear. Herein, we aimed to explore the possible mec...

    ** Wang, Dan Ma, Jishi Wang, Qin Fang, Rui Gao, Weibing Wu, Lu Cao in Tumor Biology (2016)

  7. No Access

    Article

    Mdig, a lung cancer-associated gene, regulates cell cycle progression through p27KIP1

    Mineral dust-induced gene (mdig) can accelerate cell proliferation. The aim of this study is to investigate the mechanism by which mdig regulates cell proliferation. A549 cells were transfected with siRNA spec...

    Dan Ma, Dan Guo, Wei Li, Hongwen Zhao in Tumor Biology (2015)

  8. No Access

    Article

    miR-144 suppresses the proliferation and metastasis of hepatocellular carcinoma by targeting E2F3

    MicroRNAs (miRNAs) play essential roles in the progression of hepatocellular carcinoma (HCC). miR-144 acts as a tumor suppressor in some malignancies, while its role in HCC is unclear. Here, we found that miR-...

    Tingjia Cao, Hanjun Li, Yilin Hu, Dandan Ma, Xun Cai in Tumor Biology (2014)