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Article
Open AccessCondensation of organic-inorganic vapours governs the production of ultrafine secondary marine cloud nuclei
Ultrafine secondary marine aerosol (<100 nm), formed via gas-to-particle conversion, can make an important contribution to the number of cloud condensation nuclei in the marine boundary layer. It has long been...
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Article
Two sex pheromone receptors for sexual communication in the American cockroach
Volatile sex pheromones are vital for sexual communication between males and females. Females of the American cockroach, Periplaneta americana, produce and emit two sex pheromone components, periplanone-A (PA) an...
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Article
Open AccessFamily history and gastric cancer incidence and mortality in Asia: a pooled analysis of more than half a million participants
The family history of gastric cancer holds important implications for cancer surveillance and prevention, yet existing evidence predominantly comes from case–control studies. We aimed to investigate the associ...
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Article
Metabolic engineering of Corynebacterium glutamicum CGY-PG-304 for promoting gamma-aminobutyric acid production
Gamma-aminobutyric acid is a versatile and non-protein amino acid that plays a significant role in medicine, food, and cosmetics. The synthesis of gamma-aminobutyric acid is restricted by complex metabolic mec...
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Article
MCP-1 and IL-4 encapsulated hydrogel particles with macrophages enrichment and polarization capabilities for systemic lupus erythematosus treatment
Macrophages play a pivotal role in systemic lupus erythematosus (SLE) therapy. Efforts have been made to develop multifunctional drug delivery systems capable of directing macrophage polarization. Here, we pre...
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Article
Fasn involved in the nephrotoxicity induced by polystyrene nanoplastics and the intervention of melatonin through intestinal microbiota-mediated lipid metabolism disorder
Nanoplastics (NPs) can accumulate in the kidney and cause kidney injury, but the multi-organ interaction mechanism and preventive measures of kidney injury are still unclear. In this study, in vivo (60 µg/day, 42...
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Article
Open AccessAnalysis of the stakes of the **anyang Ancient Ferry Site, Shaanxi, China
Historical records indicate that **anyang Ancient Ferry Site, dating back over three millennia to the late Shang Dynasty, has been an important transportation hub in ancient times. The use of combined wooden s...
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Article
Inhibition of STAT3-NF-κB pathway facilitates SSPH I-induced ferroptosis in HepG2 cells
Hepatocellular carcinoma (HCC), a highly lethal solid tumor, has shown responsiveness to ferroptosis inducers, presenting new avenues in cancer treatment. Our study focuses on the roles of STAT3 and Nf-κB in r...
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Article
A machine-learning-based peridynamic surrogate model for characterizing deformation and failure of materials and structures
It is necessary to determine the input features and output results when constructing a surrogate model within the data-driven neural network. Since the law of features would be restrained when the surrogate me...
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Article
Open AccessPeptostreptococcus anaerobius mediates anti-PD1 therapy resistance and exacerbates colorectal cancer via myeloid-derived suppressor cells in mice
Bacteria such as the oral microbiome member Peptostreptococcus anaerobius can exacerbate colorectal cancer (CRC) development. Little is known regarding whether these immunomodulatory bacteria also affect antitumo...
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Article
Accelerating Massively Distributed Deep Learning Through Efficient Pseudo-Synchronous Update Method
In recent years, deep learning models have been successfully applied to large-scale data analysis, including image classification, video caption, natural language processing, etc. Large-scale data analyses tak...
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Article
Managerial attention to environmental protection and corporate green innovation
We examine whether and how managerial attention to environmental protection (MAEP) affects firms’ green innovation. Using a sample of Chinese public firms in heavily polluting industries, we find a positive as...
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Article
Open AccessA comprehensive benchmarking with interpretation and operational guidance for the hierarchy of topologically associating domains
Topologically associating domains (TADs), megabase-scale features of chromatin spatial architecture, are organized in a domain-within-domain TAD hierarchy. Within TADs, the inner and smaller subTADs not only m...
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Article
Open AccessEffects of plyometric training on health-related physical fitness in untrained participants: a systematic review and meta-analysis
Plyometric training (PT) is an effective training method for improving physical fitness among trained individuals; however, its impact on health-related physical fitness in untrained participants remains ambig...
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Article
Open AccessAuthor Correction: Genome-wide analysis to uncover how Pocillopora acuta survives the challenging intertidal environment
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Article
Preparation and Mechanism of Low-Molecular-Weight Amine-Based Inhibitor that Completely Inhibits Surface Hydration of Clay Minerals
The inhibition of surface hydration is the most fundamental technical measure for controlling shale borehole stability, but little research has been conducted on the inhibition of surface hydration. In this st...
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Article
Open AccessGenome-wide analysis to uncover how Pocillopora acuta survives the challenging intertidal environment
Characterisation of genomic variation among corals can help uncover variants underlying trait differences and contribute towards genotype prioritisation in coastal restoration projects. For example, there is g...
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Article
Open AccessEvaluation of commonly used reinforcement materials for color paintings on ancient wooden architecture in China
Over recent decades, various heritage institutions have utilized a multitude of materials to reinforce the painted layers of ancient Chinese wooden architecture. In this study, we conducted a comprehensive eva...
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Article
Transport and retention of ciprofloxacin with presence of multi-walled carbon nanotubes in the saturated porous media: impacts of ionic strength and cation types
The environmental fate and risks of ciprofloxacin (CIP) in the subsurface have raised intensive concerns. Herein, the transport behaviors of CIP in both saturated quartz sand and sand/multi-walled carbon nanot...
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Article
Open AccessEP300-ZNF384 transactivates IL3RA to promote the progression of B-cell acute lymphoblastic leukemia
The EP300-ZNF384 fusion gene is an oncogenic driver in B-cell acute lymphoblastic leukemia (B-ALL). In the present study, we demonstrated that EP300-ZNF384 substantially induces the transcription of IL3RA and the...
