153,018 Result(s)
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Article
Effect of sagittal alignment on spinal cord biomechanics in the stenotic cervical spine during neck flexion and extension
Spinal cord stress and strain contribute to degenerative cervical myelopathy (DCM), while cervical kyphosis is known to negatively impact surgical outcomes. In DCM, the relationship between spinal cord biomech...
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Open AccessPlatelet-Rich Plasma Promotes the Expansion of Human Myoblasts and Favors the In Vitro Generation of Human Muscle Reserve Cells in a Deeper State of Quiescence
Stem cell therapy holds significant potential for skeletal muscle repair, with in vitro-generated human muscle reserve cells (MuRCs) emerging as a source of quiescent myogenic stem cells that can be injected t...
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Letter to the Editor
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Open AccessFactors leading to falls in transfemoral prosthesis users: a case series of prosthesis-side stumble recovery responses
Falls due to stumbling are prevalent for transfemoral prosthesis users and may lead to increased injury risk. This preliminary case series analyzes the transfemoral prosthesis user stumble recovery response to...
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Open AccessInter-joint coordination with and without dopaminergic medication in Parkinson’s disease: a case-control study
How the joints exactly move and interact and how this reflects PD-related gait abnormalities and the response to dopaminergic treatment is poorly understood. A detailed understanding of these kinematics can in...
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Open AccessIntelligent ankle–foot prosthesis based on human structure and motion bionics
The ankle–foot prosthesis aims to compensate for the missing motor functions by fitting the motion characteristics of the human ankle, which contributes to enabling the lower-limb amputees to take care of them...
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Open AccessSignal drift in diffusion MRI of the brain: effects on intravoxel incoherent motion parameter estimates
Signal drift has been put forward as one of the fundamental confounding factors in diffusion MRI (dMRI) of the brain. This study characterizes signal drift in dMRI of the brain, evaluates correction methods, a...
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Open AccessMagnetic-guided nanocarriers for ionizing/non-ionizing radiation synergistic treatment against triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a subtype of breast cancer with the worst prognosis. Radiotherapy (RT) is one of the core modalities for the disease; however, the ionizing radiation of RT has severe si...
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The Angiogenic Repertoire of Stem Cell Extracellular Vesicles: Demystifying the Molecular Underpinnings for Wound Healing Applications
Stem cells-derived extracellular vesicles (SC-EVs) have emerged as promising therapeutic agents for wound repair, recapitulating the biological effects of parent cells while mitigating immunogenic and tumorige...
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Open AccessEvolution of hadron therapy from 1935 to 2005: a personal view
Hadron therapy is today an established modality in cancer radiation therapy that, world-wide, is available in about hundred centres. About 90% of them are devoted to proton therapy and the rest also to carbon ...
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Soft, body conformable electronics for thermoregulation enabled by kirigami
在节约能源与保证生活质量的同时, 将热电设备 (TEDs) 应用于个性化的体温调节具有非常大的吸引力。直接贴附在皮肤上的热电设备能够显著降低因冷却整个环境而产生的能量浪费。然而, 在面对人体皮肤呈现的极端动态的几何形状和应变, 传统的热电设备无法贴合人体轮廓以达到最佳的体温调节效果。因此, 本文基于剪纸技术设计了一种具有出色的透气性、柔性和共形性的可穿戴式热电设备。数值分析和实验结果均表明, 本文开发的热电设备能够...
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Comprehensive Quality Analysis of Conventional and Novel Biomarkers in Diagnosing and Predicting Prognosis of Coronary Artery Disease, Acute Coronary Syndrome, and Heart Failure, a Comprehensive Literature Review
Coronary artery disease (CAD), acute coronary syndrome (ACS), and heart failure (HF) are major global health issues with high morbidity and mortality rates. Biomarkers like cardiac troponins (cTn) and natriure...
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Open AccessModeling cardiac microcirculation for the simulation of coronary flow and 3D myocardial perfusion
Accurate modeling of blood dynamics in the coronary microcirculation is a crucial step toward the clinical application of in silico methods for the diagnosis of coronary artery disease. In this work, we presen...
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Heart disease classification based on combination of PCA /ANFIS model
This study aims to create an intelligent system for the classification of electrocardiogram (ECG) signals using a combined approach of Principal Component Analysis (PCA) and the Adaptive Neuro-Fuzzy Inference ...
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Open AccessResearch Progress on Bio-inspired Flap**-Wing Rotor Micro Aerial Vehicle Development
Flap**-wing rotor (FWR) is an innovative bio-inspired micro aerial vehicle capable of vertical take-off and landing. This unique design combines active flap** motion and passive wing rotation around a vert...
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Open AccessPlate fixation of inferior ramus in pubis-ischium ramus improves mechanical stability in Tile B pelvic injures: a cadaveric biomechanical analysis and early clinical experience
Management of inferior ramus of the pubis-ischium ramus remains controversial, and related research is sparse. The main intention of this study is to describe the biomechanical and clinical outcomes of pubis-i...
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A drug-loaded flexible substrate improves the performance of conformal cortical electrodes
皮质电极是刺激和/或记录神经系统电活动的有力工具. 然而, 外科植入电极所导致的不可避免的伤口带来了与外源性物质暴露相关的细菌感染和炎症反应风险. 此外, 伤口区域的炎症可能会因细菌感染而急剧恶化. 这些后果不仅可能导致皮质电极植入失败, 还可能威胁患者生命. 在此, 我们制备了负载抗生素四环素 (TC) 和抗炎药物地塞米松 (DEX) 的细菌纤维素 (BC) 水凝胶, 并将其作为皮质电极的柔性基底. 负载的药物可...
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Open AccessDual-task improvement of older adults after treadmill walking combined with blood flow restriction of low occlusion pressure: the effect on the heart–brain axis
This study explored the impact of one session of low-pressure leg blood flow restriction (BFR) during treadmill walking on dual-task performance in older adults using the neurovisceral integration model framew...
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Jetting-based bioprinting: process, dispense physics, and applications
喷射式生物打印是一种通过无接触的按需喷射亚微升级微液滴在特定位置准确控制细胞、生长因子、药物和生物材料空间排列的高度自动化逐层制造方法。由于其极大的多功能性，喷射式生物打印已被用于组织工程和再生医学、伤口愈合和药物研发等各种应用。现阶段对于喷射式生物打印过程中发生的机制还缺乏深入的理解。本综述将全面讨论喷射式生物打印中使用的生物墨水和打印条件的物理考量。作者首先总结了不同的喷射式生物打印技术，如喷墨生物打印、激光诱...
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PET Images Enhancement Using Deep Training of Reconstructed Images with Bayesian Penalized Likelihood Algorithm
To adopt the merits of the Bayesian Penalized Likelihood (BPL) reconstruction algorithm (incl. improved contrast recovery), a deep learning ResNet model was trained to estimate BPL-like images using the non-at...
