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  1. Article

    Erratum: Safety and efficacy of plasmid DNA expressing two isoforms of hepatocyte growth factor in patients with critical limb ischemia

    Correction to: Gene Therapy advance online publication 14 January 2016; doi:10.1038/gt.2015.110 Following the online publication for this article, the authors noted that the funding information provided was in...

    M R Kibbe, A T Hirsch, F O Mendelsohn, M G Davies, H Pham, J Saucedo… in Gene Therapy (2016)

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    Article

    Safety and efficacy of plasmid DNA expressing two isoforms of hepatocyte growth factor in patients with critical limb ischemia

    VM202, a plasmid DNA that expresses two isoforms of hepatocyte growth factor, may elicit angiogenic effects that could benefit patients with critical limb ischemia (CLI). In a phase 2, double-blind trial in 52...

    M R Kibbe, A T Hirsch, F O Mendelsohn, M G Davies, H Pham, J Saucedo… in Gene Therapy (2016)

  3. Article

    Open Access

    Interleukin-8 and its receptor CXCR2 in the tumour microenvironment promote colon cancer growth, progression and metastasis

    Colorectal cancer (CRC) is a leading cause of death in the United States. Increased level of interleukin-8 (IL-8) and CXCR2 on tumours and in the tumour microenvironment has been associated with CRC growth, pr...

    Y S Lee, I Choi, Y Ning, N Y Kim, V Khatchadourian, D Yang… in British Journal of Cancer (2012)

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  4. Article

    Unraveling the sequence dynamics of the formation of genus-specific satellite DNAs in the family solanaceae

    Tandemly repeated DNAs, referred to as satellite DNAs, often occur in a genome in a genus-specific manner. However, the mechanisms for generation and evolution for these sequences are largely unknown because o...

    S-H Jo, H-M Park, S-M Kim, H H Kim, C-G Hur, D Choi in Heredity (2011)

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  5. No Access

    Article

    Polymeric gene delivery of ischemia-inducible VEGF significantly attenuates infarct size and apoptosis following myocardial infarct

    The development of clinically beneficial myocardial gene therapy has been slowed by reliance on the use of viral carriers and non-physiologic, constitutive gene expression. To specifically address these issues...

    J W Yockman, D Choi, M G Whitten, C W Chang, A Kastenmeier, H Erickson… in Gene Therapy (2009)