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    Modeling and Deorphanization of Orphan GPCRs

    Despite tremendous efforts, approximately 120 GPCRs remain orphan. Their physiological functions and their potential roles in diseases are poorly understood. Orphan GPCRs are extremely important because they m...

    Constantino Diaz, Patricia Angelloz-Nicoud… in Computational Methods for GPCR Drug Discov… (2018)