6 Result(s)
within
Cody Ashby
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessBispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
Anti-multiple myeloma B cell maturation antigen (BCMA)-specific chimeric antigen receptor (CAR) T-cell therapies represent a promising treatment strategy with high response rates in myeloma. However, durable c...
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Article
Open AccessThe spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
Deciphering Multiple Myeloma evolution in the whole bone marrow is key to inform curative strategies. Here, we perform spatial-longitudinal whole-exome sequencing, including 140 samples collected from 24 Multi...
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Article
Open AccessAuthor Correction: Accelerated single cell seeding in relapsed multiple myeloma
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-20978-y.
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Article
Open AccessThe molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
Smoldering myeloma (SMM) is associated with a high-risk of progression to myeloma (MM). We report the results of a study of 82 patients with both targeted sequencing that included a capture of the immunoglobul...
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Article
Open AccessAccelerated single cell seeding in relapsed multiple myeloma
Multiple myeloma (MM) progression is characterized by the seeding of cancer cells in different anatomic sites. To characterize this evolutionary process, we interrogated, by whole genome sequencing, 25 samples...
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Article
Open AccessDNAp: A Pipeline for DNA-seq Data Analysis
Next-generation sequencing is empowering genetic disease research. However, it also brings significant challenges for efficient and effective sequencing data analysis. We built a pipeline, called DNAp, for ana...
