5 Result(s)

Article

Bridging of host-microbiota tryptophan partitioning by the serotonin pathway in fungal pneumonia

The aromatic amino acid L-tryptophan (Trp) is essentially metabolized along the host and microbial pathways. While much is known about the role played by downstream metabolites of each pathways in intestinal h...

Giorgia Renga, Fiorella D’Onofrio, Marilena Pariano… in Nature Communications (2023)

Article

Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study

Cystic fibrosis (CF) is an autosomal recessive disorder characterized by respiratory failure due to a vicious cycle of defective Cystic Fibrosis Transmembrane conductance Regulator (CFTR) function, chronic inf...

Barbara Cellini, Gioena Pampalone, Emidio Camaioni, Marilena Pariano… in Scientific Reports (2023)

Article

A microbially produced AhR ligand promotes a Tph1-driven tolerogenic program in multiple sclerosis

Multiple sclerosis is a debilitating autoimmune disease, characterized by chronic inflammation of the central nervous system. While the significance of the gut microbiome on multiple sclerosis pathogenesis is ...

Teresa Zelante, Giuseppe Paolicelli, Francesca Fallarino… in Scientific Reports (2024)

Article

Author Correction: Bridging of host-microbiota tryptophan partitioning by the serotonin pathway in fungal pneumonia

Giorgia Renga, Fiorella D’Onofrio, Marilena Pariano… in Nature Communications (2024)