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Open AccessAuthor Correction: Bridging of host-microbiota tryptophan partitioning by the serotonin pathway in fungal pneumonia
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Article
Open AccessA microbially produced AhR ligand promotes a Tph1-driven tolerogenic program in multiple sclerosis
Multiple sclerosis is a debilitating autoimmune disease, characterized by chronic inflammation of the central nervous system. While the significance of the gut microbiome on multiple sclerosis pathogenesis is ...
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Article
Open AccessDual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study
Cystic fibrosis (CF) is an autosomal recessive disorder characterized by respiratory failure due to a vicious cycle of defective Cystic Fibrosis Transmembrane conductance Regulator (CFTR) function, chronic inf...
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Article
Open AccessBridging of host-microbiota tryptophan partitioning by the serotonin pathway in fungal pneumonia
The aromatic amino acid L-tryptophan (Trp) is essentially metabolized along the host and microbial pathways. While much is known about the role played by downstream metabolites of each pathways in intestinal h...
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Article
slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells
Dendritic cells (DCs) initiate adaptive immune responses to cancer cells by activating naive T lymphocytes. 6-sulfo LacNAc+ DCs (slanDCs) represent a distinct population of circulating and tissue proinflammatory ...