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Characterization of a novel human BFL-1-specific monoclonal antibody
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Open AccessPreclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors
Targeting cell division by chemotherapy is a highly effective strategy to treat a wide range of cancers. However, there are limitations of many standard-of-care chemotherapies: undesirable drug toxicity, side-...
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Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence
Cell death, cell cycle arrest and cellular senescence are three distinct cellular responses that can be induced by oncogene activation and diverse anti-cancer agents, and this often requires the action of the ...