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    Structural variants shape driver combinations and outcomes in pediatric high-grade glioma

    We analyzed the contributions of structural variants (SVs) to gliomagenesis across 179 pediatric high-grade gliomas (pHGGs). The most recurrent SVs targeted MYC isoforms and receptor tyrosine kinases (RTKs), incl...

    Frank P. B. Dubois, Ofer Shapira, Noah F. Greenwald, Travis Zack… in Nature Cancer (2022)