2 Result(s)
within
Claire J. Schwab
English
Hematology
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Article
Open AccessSH2B3 inactivation through CN-LOH 12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain
In more than 30% of B-cell precursor acute lymphoblastic leukaemia (B-ALL), chromosome 21 sequence is overrepresented through aneuploidy or structural rearrangements, exemplified by intrachromosomal amplificat...
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Article
Open AccessWhole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemia
Childhood B-cell acute lymphoblastic leukaemia (B-ALL) is characterised by recurrent genetic abnormalities that drive risk-directed treatment strategies. Using current techniques, accurate detection of such ab...
