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Myoloid-Related Protein 8, an Endogenous Ligand of Toll-Like Receptor 4, Is Involved in Epileptogenesis of Mesial Temporal Lobe Epilepsy Via Activation of the Nuclear Factor-κB Pathway in Astrocytes

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  1. Article

    Open Access

    Familial SYN1 variants related neurodevelopmental disorders in Asian pediatric patients

    SYN1 encodes synapsin I, which is a neuronal phosphoprotein involving in regulating axonogenesis and synaptogenesis. Variants in the gene have been associated with X-linked neurodevelopmental disorders in recent ...

    Juan **ong, Haolin Duan, Shimeng Chen, Miriam Kessi, Fang He… in BMC Medical Genomics (2021)

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  2. Article

    Open Access

    First case report of cerebral folate deficiency caused by a novel mutation of FOLR1 gene in a Chinese patient

    Cerebral folate deficiency (CFD) is a neurological disease, hallmarked by remarkable low concentrations of 5-methyltetrahydrofolic acid (5-MTHF) in cerebrospinal fluid (CSF). The primary causes of CFD include ...

    Ciliu Zhang, **aolu Deng, Yafei Wen, Fang He, Fei Yin, **g Peng in BMC Medical Genetics (2020)

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  3. Article

    Open Access

    The patterns of response of 11 regimens for infantile spasms

    Infantile spasms (ISs) is a devastating form of an early infantile epileptic encephalopathy. The patterns of response of multiple regimens, and the difference in response rates for the cases who receive first-...

    Leilei Mao, Miriam Kessi, Pan Peng, Fang He, Ciliu Zhang, Lifen Yang… in Scientific Reports (2020)

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  4. Article

    Open Access

    Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction

    Tumor necrosis factor-α (TNF-α), a proinflammatory cytokine, is capable of activating the small GTPase RhoA, which in turn contributes to endothelial barrier dysfunction. However, the underlying signaling mechani...

    **g Peng, Fang He, Ciliu Zhang, **aolu Deng, Fei Yin in Journal of Neuroinflammation (2011)

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