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    Article

    Myoloid-Related Protein 8, an Endogenous Ligand of Toll-Like Receptor 4, Is Involved in Epileptogenesis of Mesial Temporal Lobe Epilepsy Via Activation of the Nuclear Factor-κB Pathway in Astrocytes

    The role of Toll-like receptor 4 (TLR4) in the activation of innate immunity has been extensively studied in the past several years. Here, we are the first to report that myeloid-related protein 8 (MRP8), an e...

    Na Gan, Lifen Yang, Ahmed Omran, **g Peng, Liwen Wu, Fang He in Molecular Neurobiology (2014)

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    Article

    Role of ventriculoperitoneal shunt surgery in grade IV tubercular meningitis with hydrocephalus

    Hydrocephalus is a common complication of tuberculous meningitis (TBM) in children. The role of ventriculoperitoneal shunt (VPS) placement in grade IV patients is controversial. The aim of this study is to inv...

    **g Peng, **aolu Deng, Fang He, Ahmed Omran, Ciliu Zhang in Child's Nervous System (2012)

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    Open Access

    Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction

    Tumor necrosis factor-α (TNF-α), a proinflammatory cytokine, is capable of activating the small GTPase RhoA, which in turn contributes to endothelial barrier dysfunction. However, the underlying signaling mechani...

    **g Peng, Fang He, Ciliu Zhang, **aolu Deng, Fei Yin in Journal of Neuroinflammation (2011)