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  1. Article

    Open Access

    Coadaptation fostered by the SLIT2-ROBO1 axis facilitates liver metastasis of pancreatic ductal adenocarcinoma

    To explore the mechanism of coadaptation and the potential drivers of pancreatic ductal adenocarcinoma (PDAC) metastasis to the liver, we study key molecules involved in this process and their translational va...

    Qing Li, **ao-**n Zhang, Li-Peng Hu, Bo Ni, Dong-Xue Li, Xu Wang in Nature Communications (2023)

  2. Article

    Open Access

    Identification of a subset of immunosuppressive P2RX1-negative neutrophils in pancreatic cancer liver metastasis

    The immunosuppressive microenvironment that is shaped by hepatic metastatic pancreatic ductal adenocarcinoma (PDAC) is essential for tumor cell evasion of immune destruction. Neutrophils are important componen...

    Xu Wang, Li-Peng Hu, Wei-Ting Qin, Qin Yang, De-Yu Chen, Qing Li in Nature Communications (2021)