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    Article

    Identification of a Novel Mutation in the Presenilin 1 Gene in a Chinese Alzheimer’s Disease Family

    This study has identified a gene mutation in a Chinese family with Alzheimer’s disease (AD). Family members were screened by a set of medical examinations and neuropsychological tests. Their DNA was extracted ...

    Bo Deng, Yan Lian, **n Wang, Fan Zeng, Bin Jiao, Ye-Ran Wang in Neurotoxicity Research (2014)

  2. Article

    Open Access

    An N-terminal antibody promotes the transformation of amyloid fibrils into oligomers and enhances the neurotoxicity of amyloid-beta: the dust-raising effect

    Senile plaques consisting of amyloid-beta (Aβ) are the major pathological hallmark of Alzheimer’s disease (AD) and have been the primary therapeutic target. Immunotherapies, which are designed to remove brain ...

    Yu-Hui Liu, **an-Le Bu, Chun-Rong Liang, Ye-Ran Wang in Journal of Neuroinflammation (2015)