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  1. Article

    Open Access

    Study on the failure mechanism of high-temperature granite under two cooling modes

    In the geothermal development of hot dry rock (HDR), both the drilling of the wellbore and the heat exchange of the heat reservoir involve the effects of different cold and hot conditions on the high-temperatu...

    Chun Li, Gan Feng, **nran Zhang, Chunwang Zhang, Yaoqing Hu, Tao Meng in Scientific Reports (2024)

  2. Article

    Open Access

    Adherence to the dietary approaches to stop hypertension diet reduces the risk of diabetes mellitus: a systematic review and dose-response meta-analysis

    Despite several epidemiological studies reporting a significant association between adherence to the Dietary Approaches to Stop Hypertension (DASH) diet and the risk of diabetes mellitus, the results remain co...

    **yan Quan, **aoming Shen, Chun Li, Yayuan Li, Tiangang Li, Baifan Chen in Endocrine (2024)

  3. Article

    Open Access

    Robust pose estimation which guarantees positive depths

    In the area of 3D computer vision, the ability to estimate pose between two cameras under high noise levels while maintaining small reprojection errors reflects the robustness of such pose estimation algorithm...

    Chun Li, John E. McInroy in Scientific Reports (2023)

  4. Article

    Open Access

    Performance boost for bismuth telluride thermoelectric generator via barrier layer based on low Young’s modulus and particle sliding

    The lack of desirable diffusion barrier layers currently prohibits the long-term stable service of bismuth telluride thermoelectric devices in low-grade waste heat recovery. Here we propose a new design princi...

    Yuxin Sun, Fengkai Guo, Yan Feng, Chun Li, Yongchun Zou in Nature Communications (2023)

  5. Article

    Open Access

    On-body non-invasive glucose monitoring sensor based on high figure of merit (FoM) surface plasmonic microwave resonator

    High-figure of merit (FoM) plasmonic microwave resonator is researched as a non-invasive on-body sensor to monitor the human body's blood glucose variation rate in adults for biomedical applications, e.g., dia...

    Farzad Soltanian, Mehdi Nosrati, Saleh Mobayen, Chuan-Chun Li in Scientific Reports (2023)

  6. Article

    Open Access

    A polycistronic system for multiplexed and precalibrated expression of multigene pathways in fungi

    Synthetic biology requires efficient systems that support the well-coordinated co-expression of multiple genes. Here, we discover a 9-bp nucleotide sequence that enables efficient polycistronic gene expression...

    Qun Yue, Jie Meng, Yue Qiu, Miaomiao Yin, Liwen Zhang in Nature Communications (2023)

  7. Article

    Open Access

    Prevalence, risk factors, and prognosis of central nervous system manifestations in antiphospholipid syndrome

    The central nervous system (CNS) is considered as one of the most frequently affected organs in antiphospholipid syndrome (APS). This study investigated the prevalence of CNS manifestations in APS and associat...

    Meige Liu, Gongming Li, **aodong Song, Yangyi Fan, Chun Li in Scientific Reports (2023)

  8. Article

    Open Access

    Potassium-rich mining waste addition can shorten the composting period by increasing the abundance of thermophilic bacteria during high-temperature periods

    Conventional compost sludge has a long fermentation period and is not nutrient rich. Potassium-rich mining waste was used as an additive for aerobic composting of activated sludge to make a new sludge product....

    **ao-jun Huo, YanZhou, Min-jie Chen, Jian-lin Zhou, Chun-li Zheng in Scientific Reports (2023)

  9. Article

    Open Access

    A new long-snouted marine reptile from the Middle Triassic of China illuminates pachypleurosauroid evolution

    Sauropterygia is the largest, most successful group of Mesozoic marine diapsids, spanning from the late Early Triassic to the Late Cretaceous. Plesiomorphic for sauropterygians, pachypleurosauroids are importa...

    Guang-Hui Xu, Qing-Hua Shang, Wei Wang, Yi Ren, Hong Lei in Scientific Reports (2023)

  10. Article

    Open Access

    Assessment of a three-axis on-rotor sensing performance for machining process monitoring: a case study

    Online monitoring of cutting conditions is essential in intelligent manufacturing, and vibrations are one of the most effective signals in monitoring machining conditions. Generally, traditional wired accelero...

    Chun Li, Zhexiang Zou, Kaibo Lu, Hongjun Wang, Robert Cattley in Scientific Reports (2022)

  11. Article

    Open Access

    Superelastic graphene aerogel-based metamaterials

    Ultralight, ultrastrong, and supertough graphene aerogel metamaterials combining with multi-functionalities are promising for future military and domestic applications. However, the unsatisfactory mechanical p...

    Mingmao Wu, Hongya Geng, Yajie Hu, Hongyun Ma, Ce Yang in Nature Communications (2022)

  12. Article

    Open Access

    Low-dose metformin targets the lysosomal AMPK pathway through PEN2

    Metformin, the most prescribed antidiabetic medicine, has shown other benefits such as anti-ageing and anticancer effects14. For clinical doses of metformin, AMP-activated protein kinase (AMPK) has a major role ...

    Teng Ma, **ao Tian, Baoding Zhang, Mengqi Li, Yu Wang, Chunyan Yang, Jianfeng Wu in Nature (2022)

  13. No Access

    Article

    Evidence for the association of triatomic molecules in ultracold 23Na40K + 40K mixtures

    Ultracold assembly of diatomic molecules has enabled great advances in controlled chemistry, ultracold chemical physics and quantum simulation with molecules13. Extending the ultracold association to triatomic m...

    Huan Yang, **n-Yao Wang, Zhen Su, ** Cao, De-Chao Zhang, Jun Rui, Bo Zhao in Nature (2022)

  14. Article

    Open Access

    Vitamin D suppresses bleomycin-induced pulmonary fibrosis by targeting the local renin–angiotensin system in the lung

    Idiopathic pulmonary fibrosis (IPF) is a severe disorder leading to progressive and irreversible loss of pulmonary function. In this study we investigated the anti-fibrotic effect of vitamin D using a mouse mo...

    Jianjun Chang, Hongguang Nie, **n Ge, Jie Du, Weicheng Liu, Xue Li in Scientific Reports (2021)

  15. Article

    Open Access

    Topographical map** of the mechanical characteristics of the human neurocranium considering the role of individual layers

    The site-dependent load-deformation behavior of the human neurocranium and the load dissipation within the three-layered composite is not well understood. This study mechanically investigated 257 human frontal...

    Johann Zwirner, Sarah Safavi, Mario Scholze, Kai Chun Li in Scientific Reports (2021)

  16. Article

    Open Access

    Pathway engineering in yeast for synthesizing the complex polyketide bikaverin

    Fungal polyketides display remarkable structural diversity and bioactivity, and therefore the biosynthesis and engineering of this large class of molecules is therapeutically significant. Here, we successfully...

    Meng Zhao, Yu Zhao, Mingdong Yao, Hala Iqbal, Qi Hu, Hong Liu in Nature Communications (2020)

  17. Article

    Open Access

    Deterministic culturing of single cells in 3D

    Models using 3D cell culture techniques are increasingly accepted as the most biofidelic in vitro representations of tissues for research. These models are generated using biomatrices and bulk populations of c...

    Rohil Jain, Shirisha Chittiboyina, Chun-Li Chang, Sophie A. Lelièvre in Scientific Reports (2020)

  18. Article

    Open Access

    Influence of Chronic Ethanol Consumption on Apoptosis and Autophagy Following Transient Focal Cerebral Ischemia in Male Mice

    Stroke remains one of the leading causes of permanent disability and death worldwide. Apoptosis and autophagy are two key elements involved in ischemic brain damage. Ethanol is a commonly used and abused chemi...

    Chun Li, Jiyu Li, Guodong Xu, Hong Sun in Scientific Reports (2020)

  19. Article

    Open Access

    Antiviral activity of iridoid glycosides extracted from Fructus Gardeniae against influenza A virus by PACT-dependent suppression of viral RNA replication

    Epidemic and pandemic influenza A virus (IAV) poses a significant threat to human populations worldwide. Iridoid glycosides are principal bioactive components from the Gardenia jasminoides J. Ellis fruit that exh...

    Shanshan Guo, Lei Bao, Chun Li, **g Sun, Ronghua Zhao, **aolan Cui in Scientific Reports (2020)

  20. Article

    Open Access

    Targeting Forward and Reverse EphB4/EFNB2 Signaling by a Peptide with Dual Functions

    The tyrosine kinase receptor EphB4 is frequently overexpressed in ovarian and other solid tumors and is involved in interactions between tumor cells and the tumor microenvironment, contributing to metastasis. ...

    Chiyi **ong, Yunfei Wen, Jun Zhao, Dengke Yin, Lingyun Xu in Scientific Reports (2020)

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