45 Result(s)
within
Chun-Li **ao
Microbiology
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Article
Recent advances in lycopene and germacrene a biosynthesis and their role as antineoplastic drugs
Sesquiterpenes and tetraterpenes are classes of plant-derived natural products with antineoplastic effects. While plant extraction of the sesquiterpene, germacrene A, and the tetraterpene, lycopene suffers sup...
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Article
The effect of extracellular polymeric substances on MICP solidifying rare earth slags and stabilizing Th and U
Microbially induced carbonate precipitation (MICP) has been used to cure rare earth slags (RES) containing radionuclides (e.g. Th and U) and heavy metals with favorable results. However, the role of microbial ...
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Open AccessAbiotic factors and endophytes co-regulate flavone and terpenoid glycoside metabolism in Glycyrrhiza uralensis
Recently, endorhizospheric microbiota is realized to be able to promote the secondary metabolism in medicinal plants, but the detailed metabolic regulation metabolisms and whether the promotion is influenced b...
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Open AccessImplementing a novel capture and ligation probe-PCR method in mass screen and treatment to support malaria elimination efforts in the China-Myanmar border region
Mass screening and treatment (MSAT) for malaria elimination lacks an ideal diagnostic tool to allow sensitive and affordable test of the target population in the field. This study evaluated whether Capture and...
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New species of Leccinum from Southwest China
Species of Leccinum Gray are widely distributed in the world and have very important ecological and economic values. However, due to the lack of molecular data and extensive sampling, the species diversity of Lec...
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Molecular Characterization of Distinct Fungal Communities in the Soil of a Rare Earth Mining Area
The exploitation of ion-absorbed rare earth elements (REEs) has caused serious ecological destruction and environmental pollution. Effects on soil fungal structure and diversity exerted by mining activities ar...
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Immobilization of d-allulose 3-epimerase into magnetic metal–organic framework nanoparticles for efficient biocatalysis
d-allulose is a rare low-calorie sugar that has many fundamental biological functions. d-allulose 3-epimerase from Agrobacterium tumefaciens (AT-DAEase) catalyzes the conversion of d-fructose to d-allulose. The e...
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Article
Advenella mandrilli sp. nov., a bacterium isolated from the faeces of Mandrillus sphinx
A novel Gram-negative strain WQ 585T, isolated from the faeces of mandrills (Mandrillus sphinx) collected at Yunnan Wild Animal Park, Yunnan province, China, was subjected to a polyphasic taxonomic study. Phyloge...
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Open AccessIntensive surveillance, rapid response and border collaboration for malaria elimination: China Yunnan’s ‘‘3 + 1’’strategy
Eliminating malaria and preventing re-establishment of malaria transmission in border areas requires universal coverage of malaria surveillance and a rapid response to any threats (i.e. malaria cues) of re-est...
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Article
Endophytes: the novel sources for plant terpenoid biosynthesis
Terpenoids are natural compounds predominantly present in plants. They have many pharmaceutical and/or nutritional functions, and have been widely applied in medical, food, and cosmetics industries. Recently, ...
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Open AccessEvaluation of fecal microbiota transplantation in Parkinson's disease patients with constipation
Parkinson’s disease (PD) is a neurodegenerative disorder and 70–80% of PD patients suffer from gastrointestinal dysfunction such as constipation. We aimed to assess the efficacy and safety of fecal microbiota ...
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Open AccessIntelligent microbial cell factory with genetic pH shooting (GPS) for cell self-responsive base/acid regulation
In industrial fermentation, pH fluctuation resulted from microbial metabolism influences the strain performance and the final production. The common way to control pH is adding acid or alkali after probe detec...
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Open AccessAssessment and molecular characterization of Bacillus cereus isolated from edible fungi in China
Bacillus cereus is a foodborne pathogen commonly found in nature and food and can cause food spoilage and health issues. Although the prevalence of B. cereus in foods has been reported worldwide, the extent of co...
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Open AccessEffects of ccpA gene deficiency in Lactobacillus delbrueckii subsp. bulgaricus under aerobic conditions as assessed by proteomic analysis
Aerobic growth provides benefits in biomass yield and stress tolerance of Lactobacillus delbrueckii subsp. bulgaricus (L. bulgaricus). Catabolite control protein A (CcpA) is a master regulator involved in the aer...
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Tuning the pH profile of β-glucuronidase by rational site-directed mutagenesis for efficient transformation of glycyrrhizin
In this study, we aimed to shift the optimal pH of acidic β-glucuronidase from Aspergillus oryzae Li-3 (PGUS) to the neutral region by site-directed mutagenesis, thus allowing high efficient biotransformation of ...
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Article
Engineering and manipulation of a mevalonate pathway in Escherichia coli for isoprene production
Isoprene is a useful phytochemical with high commercial values in many industrial applications including synthetic rubber, elastomers, isoprenoid medicines, and fossil fuel. Currently, isoprene is on large sca...
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Open AccessRenewable production of high density jet fuel precursor sesquiterpenes from Escherichia coli
Aviation fuels are an important target of biofuels research due to their high market demand and competitive price. Isoprenoids have been demonstrated as good feedstocks for advanced renewable jet fuels with h...
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Article
Open AccessGene repression via multiplex gRNA strategy in Y. lipolytica
The oleaginous yeast Yarrowia lipolytica is a promising microbial cell factory due to their biochemical characteristics and native capacity to accumulate lipid-based chemicals. To create heterogenous biosynthesis...
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Article
Open AccessEndogenous lycopene improves ethanol production under acetic acid stress in Saccharomyces cerevisiae
Acetic acid, generated from the pretreatment of lignocellulosic biomass, is a significant obstacle for lignocellulosic ethanol production. Reactive oxidative species (ROS)-mediated cell damage is one of import...
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A novel DMAPP-responding genetic circuit sensor for high-throughput screening and evolving isoprene synthase
High-throughput screening is a popular tool for collating biological data which would otherwise require the use of excessive resources. In this study, an artificial genetic circuit sensor responding to dimethy...
