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1,466 Result(s)
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Article
Effect of graphene addition on activation and kinetic properties of La–Mg–Ni-based hydrogen storage alloys
The La1.7Pr0.3Mg16Ni hydrogen storage alloy was prepared by medium-frequency induction melting, and then the composite hydrogen storage alloy powder of La1.7Pr0.3Mg16Ni + x wt.% (x = 0, 2, 4, and 6) graphene was ...
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Article
ROCK1 inhibition improves wound healing in diabetes via RIPK4/AMPK pathway
Refractory wounds are a severe complication of diabetes mellitus that often leads to amputation because of the lack of effective treatments and therapeutic targets. The pathogenesis of refractory wounds is com...
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Article
Open AccessIL-37d suppresses Rheb-mTORC1 axis independently of TCS2 to alleviate alcoholic liver disease
Tuberous sclerosis complex 2 (TSC2) crucially suppresses Rheb activity to prevent mTORC1 activation. However, mutations in TSC genes lead to mTORC1 overactivation, thereby causing various developmental disorde...
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Association between obstructive sleep apnea severity and depression risk: a systematic review and dose-response meta-analysis
Obstructive sleep apnea (OSA) has received considerable attention as a potential risk factor for depressive symptoms. The systematic review was conducted to confirm the dose‒response connection between OSA sev...
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Article
Ultrahard X-ray multifunctional application beamline at the SSRF
The ultrahard X-ray multifunctional application beamline (BL12SW) is a phase-II beamline project at the Shanghai Synchrotron Radiation Facility. The primary X-ray techniques used at the beamline are high-energ...
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Article
Synthesis, Crystal Structures, In Vitro Cytostatic Activity and DFT Studies of Four Organotin(IV) Complexes Derived From Schiff-Base Carboxylic Acid
Four triorganotin(IV) complexes, [(Ph3Sn)2L] (1), [(Et3Sn)2L]n (2), [(Me3Sn)2L] n (3), [(Me3Sn)3L(µ2-OH)] n (4) [H2L = 5-[(9-anthracenylmethylene)amino]-isophthalic acid], have been synthesized and characterized ...
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Article
A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Open AccessCorrection: Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-κB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar macrophages
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Article
Transplantation of olfactory mucosa mesenchymal stromal cells repairs spinal cord injury by inducing microglial polarization
Animal studies
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Article
A novel route to enhance high-temperature mechanical property and thermal shock resistance of low-carbon MgO–C bricks by introducing ZrSiO4
Conventional MgO–C bricks (graphite content > 14 wt.%) produce a great deal of greenhouse gas emission, while low-carbon MgO–C bricks have serious thermal shock resistance during high-temperature service. To e...
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Article
Chinese Medicine Prolongs Overall Survival of Chinese Patients with Advanced Gastric Cancer: Treatment Pattern and Survival Analysis of a 20-Year Real-World Study
To describe the treatment patterns and survival status of advanced gastric cancer (AGC) in China in the past two decades, and objectively evaluate the impact of standardized Chinese medicine (CM) treatment on ...
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Article
Were oxygen isotopes of hydrothermally altered minerals just elevated by the 18O-enriched water? Theoretical inversion with thermodynamics and kinetics
For a long time, it has been implicitly believed that oxygen isotopes of hydrothermally altered rocks and/or minerals were only elevated by the heavy water enriched in 18O from the modern geothermal and/or fossil...
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Article
Open AccessWhat are the differences in paraspinal muscle morphometry among degenerative spondylolisthesis patients, isthmic spondylolisthesis patients, and healthy individuals? A propensity score matching analysis
To compare the morphometry of paraspinal muscles in patients with degenerative spondylolisthesis (DS), isthmic spondylolisthesis (IS), and healthy individuals.
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Article
m6A demethylation of FOSL1 mRNA protects hepatoma cells against necrosis under glucose deprivation
Stress-adaptive mechanisms enabling cancer cells to survive under glucose deprivation remain elusive. N6-methyladenosine (m6A) modification plays important roles in determining cancer cell fate and cellular stres...
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Article
Bevacizumab induces ferroptosis and enhances CD8+ T cell immune activity in liver cancer via modulating HAT1 and increasing IL-9
Bevacizumab is a recombinant humanized monoclonal immunoglobulin (Ig) G1 antibody of VEGF, and inhibits angiogenesis and tumor growth in hepatocellular carcinoma (HCC). Ferroptosis, a new form of regulated cel...
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Article
Open AccessSignal enhancement ratio of multi-phase contrast-enhanced MRI: an imaging biomarker for survival in pancreatic adenocarcinoma
To evaluate signal enhancement ratio (SER) for tissue characterization and prognosis stratification in pancreatic adenocarcinoma (PDAC), with quantitative histopathological analysis (QHA) as the reference stan...
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Article
Preparation and characteristics of the O3+-ion-implanted and femtosecond laser-ablated waveguide in the high-gain Nd3+-doped laser glass
In the work, the planar and ridge waveguides are fabricated by the combination of ion implantation and femtosecond laser ablation in the high-gain Nd3+-doped laser glass. The species, energy, and dose of ion impl...
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Open AccessRisk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis: a nationwide retrospective study in China
Pediatric antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a life-threatening systemic vasculitis featured by liability to renal involvement. However, there are few studies on the risk factor...
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Article
Open AccessThoracolumbar fractures patients undergoing posterior pedicle screw fixation can benefit from drainage
To explore whether it is necessary to put drain tubes after posterior pedicle screw fixation of thoracolumbar fractures.
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Real-time analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics
Large-scale imaging of neuronal activities is crucial for understanding brain functions. However, it is challenging to analyze large-scale imaging data in real time, preventing closed-loop investigation of neu...